摘要
目的:探讨C反应蛋白(CRP)、血钙和胸腔积液在早期预测重症急性胰腺炎(SAP)中的价值。方法:回顾性分析我院确诊为急性胰腺炎且临床资料完整的患者48例,依据2003年中华医学会消化病学分会胰腺病学组制定的"中国急性胰腺炎诊治指南"分为轻症急性胰腺炎(mild acutepancreatitis,MAP)组和重症急性胰腺炎(severe acute pancreatitis,SAP)组,两组资料具有可比性,分析患者发病第1、3 d血清钙和CRP水平及入院时是否有胸腔积液,并对这3项指标预测SAP的价值进行评估。结果:同时期SAP组与MAP组相比CRP及血钙水平差异具有统计学意义(P<0.05),对CRP升高(≥150 mg/L)、血钙降低(≤1.75mmol/L)、胸腔积液和三者同时存在这四项参数分别进行分析,发现四者均可作为SAP的独立预测指标,其中CRP升高,血钙降低合并胸腔积液预测SAP最有价值。结论:CRP、血钙和胸腔积液是经济、有用、简单的指标,有助于早期预测急性胰腺炎的严重程度。
Objective： To investigate the value of C-reactive protein （CRP） , serum calcium and pleural effusion levels in predicting the sever- ity of severe acute pancreatitis（SAP） in its early stage. Methods：Retro- spective analysis was performed in 48 patients with acute panereatitis undergone final diagnosis in our hospital between Jan. 2010 and Dec. 2010. The patients were allocated to either mild acute pancreatitis （MAP） group or SAP group on basis of the Guidelines for Clinical Diagnosis and Classification of Acute Pancreatitis developed in 2003 by the Digestive Disease Branch of Chinese Medical Association. The levels of CRP and serum calcium were measured on the day 1 and day 3 and the pleural effusion levels were determined after admission for estimating the severity of SAP. The data for the two groups were also analyzed and compared. Results ： There were significant differences in CRP and serum calcium levels detected at the same interval between SAP group and MAP group （ P 〈 0.05 ）. Al- though single level of CRP （ elevated ） , serum calcium （ decreased ） and pleural effusion or integrated level reference of the three respectively suggested predicative value, yet elevated CRP and decreased serum calcium levels associated with pleural effusion were most sensitive in predicting the severity of SAP. Conclusion ： Determination of the CPR, serum calcium and pleural effusion levels appears economic, simple and valuable in predicting the severity of acute pancreatitis in its early stage.
出处
《皖南医学院学报》
CAS
2013年第3期213-215,共3页
Journal of Wannan Medical College
关键词
C反应蛋白
血钙
胸腔积液
急性胰腺炎
早期预测严重度
C-reactive protein
serum calcium
pleural effusion
acute pancreatits
mild acute panereatitis
severity
