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甲状腺过氧化物酶抗体对妊娠结局及后代智力影响的研究进展 被引量:2

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摘要 甲状腺过氧化物酶(TPO)在甲状腺激素合成过程中催化碘离子氧化、酪氨酸碘化及碘化酪氨酸偶联,是甲状腺激素合成的关键酶。TPOAb是TPO的特异性抗体,TPOAb与TPO结合后可抑制TP0活性,减少甲状腺激素的合成,甚至导致甲状腺疾病发生。国外文献报道,妊娠期妇女TPOAb阳性率为15.3%~16%;国内研究显示,妊娠前半期TPOAb阳性率为9.17%。
作者 龙玉 唐卉
出处 《蛇志》 2013年第2期219-221,共3页 Journal of Snake
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参考文献38

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二级参考文献77

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