摘要
目的 建立和了解成年大鼠纹状体、边缘区和苍白球在脑中的立体形态和相互关系 .方法 在大鼠脑的连续冠状切片 Nissl染色的基础上通过 Onyx2超级图形工作站应用计算机图形技术进行了三维重建 .结果 边缘区位于尾壳核和苍白球之间 ;尾壳核的立体形态呈近似的内凹半球形 ,从嘴侧到尾侧随着脑平面的增宽尾壳核逐渐向外侧 (即靠近外轮廓的方向 )移位 ,体积为 (37.77± 9) m m3,最大嘴尾径为 6 .2mm;最大背腹径为 4.9m m;最大内外径为 3.5 2 9mm.苍白球呈块形 ,位于尾壳核的内侧 ,除内侧外其他三个方向均被尾壳核包绕 ,体积为 (4.0 5± 0 .0 6 ) mm3,最大嘴尾径为 4.41mm,最大背腹径为 2 .6 45 mm ,最大内外径为 1.5 44 m m.边缘区呈现一个片状扇形结构 ,体积为 (0 .48± 0 .0 2 ) mm3,最大嘴尾径为 1.6 m m,最大背腹径为 2 .15 8m m,最大内外径为0 .17mm;同尾壳核和苍白球一样从嘴侧到尾侧随着脑平面的增宽边缘区亦逐渐向外侧 (即靠近外轮廓的方向 )移位 ,其移位的幅度亦明显大于脑平面增宽的幅度 ;整个边缘区从嘴侧到尾侧呈均匀变化 ,其片状逐渐变宽 ,长度 (背腹径 )逐渐变小 ,从而形成一个盘状结构 .结论 建立了大鼠脑纹状体。
AIM To construct the three dimensional (3 D) stereotactic morphology of the corpus striatum, marginal division and globus pallidus in an adult rat brain. METHODS The 3-D organization of the rat striatum and globus pallidus was studied with Nissl staining and computer 3D reconstruction technique after serial coronal sections of the adult rat brain were examined. RESULTS The marginal division(MrD)was located between the caudate putamen(CPu)and the globus pallidus(GP). The caudate putamen resembled a thick shell with a volume of (37.77±9) mm 3, a maximum rostral caudate axis of 6.2 mm, a maximum dorsal ventral axis of 4.9 mm, and a widest axis(the diameter at lateral medial coronal brain section )of 3.53 mm. The caudate putamen moved progressively toward the external part(closed to the outer contour)from the rostral section to the caudal one. Globus pallidus was located medially to the caudate putamen and was covered by the caudate putamen. The globus pallidus was potato shaped, with a volume of (4.05±0.06) mm 3, a maximum rostral caudate axis of 4.41 mm, a maximum dorsal ventral axis of 2.65 mm, and a widest axis(the diameter at lateral medial coronal brain section)of 1.54 mm. The marginal division was a flat fan shaped structure with a volume of (0.48±0.02) mm 3, a maximum rostral caudate axis of 1.6 mm, a maximum dorsal ventral axis of 2.158 mm, and a widest axis (the diameter at lateral medial coronal brain section) of 0.17 mm. The marginal division also moved progressively externally (closed to the outer contour) from the rostral section to the caudate section, but its scope was larger than that of others. The whole marginal division changed evenly from the rostral section to the caudate one. Its flat structure widened progressively and its dorsal ventral diameter narrowed gradually and became plate shaped. CONCLUSION By the computer 3D technique, a 3 D stereotactic morphology of the corpus striatum, marginal division and globus pallidus was thus reconstructed.
出处
《第四军医大学学报》
2000年第8期924-928,共5页
Journal of the Fourth Military Medical University
关键词
纹状体
边缘区
尾壳核
苍白球
计算机三维重建
striatum
marginal division
caudate putamen
globus pallidus
computer
three dimension reconstruction
