摘要
目的分析裂头蚴病患者的临床特点,以提高对该病的认识。方法回顾性分析中山大学附属第三医院2002年8月-2011年5月确诊的25例裂头蚴病患者的流行病学资料、临床表现、辅助检查和诊治情况。结果25例患者中,23例有明确的流行病学史,其中22例为食源性感染,1例为接触性感染;临床表现为中枢神经型14例、皮肤型7例、内脏型3例、眼裂头蚴病1例。25例患者实验室检查结果显示,3例内脏型患者的嗜酸粒细胞均升高,其他22例患者中仅1例嗜酸粒细胞升高;23例行寄生虫抗体全套检查,其中22例患者裂头蚴抗体阳性;14例中枢型患者,磁共振成像(MRI)检查均可见病灶;11例患者行病灶手术切除或活检术,其中8例可见虫体。该病首诊误诊率80%。经治疗后18例治愈,7例症状缓解。结论食源性感染成为裂头蚴病的重要传播途径,临床表现以中枢型为主;嗜酸粒细胞检测正常不能排除该病,血清学检查有重要诊断意义。
Objective To analyse the clinical features of sparganosis patients and improve cognition in the disease. Methods The epidemic data, clinical manifestations, auxiliary examinations, diagnosis and treatments of 25 sparganosis patients in the hospital were retrospectively analyzed. Results Among the 23 patients with definite epidemicological data , 22 cases were food-borne, one case of contact infection. According to the clinical manifestation, there were 14 cases of central nervous system （CNS） sparganosis, 7 cases of cutaneous sparganosis, 3 cases of visceral sparganosis and 1 case of ocular sparganosis. Eosinophilia in peripheral blood was found in 4 cases including the 3 cases of visceral sparganosis. 22 patients were diagnosed by serologic IgG antibody test. MRI showed positive finding in all CNS sparganosis patients. 11 cases received surgical excision or biopsy, worms were found in 8 cases. 80% of the cases were once misdiagnosed by other disorders. 18 patients were cured and 7 alleviated after treatment. Conclusion Sparganosis is mostly a food-borne infection, more involving central nervous system. Serologic test is important for diagnosis, and eosinophilia is uncommon.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
2013年第3期218-220,共3页
Chinese Journal of Parasitology and Parasitic Diseases
关键词
裂头蚴病
流行病学
临床特征
诊断
Sparganosis
Epidemiology
Clinical feature
Diagnosis
