期刊文献+

Follow-up of children born after intracytoplasmic sperm injection with epididymal and testicular spermatozoa 被引量:5

Follow-up of children born after intracytoplasmic sperm injection with epididymal and testicular spermatozoa
原文传递
导出
摘要 Background To evaluate the safety of intracytoplasmic sperm injection (ICSI) with epididymal or testicular sperm, this study compared children born after ICSI treatment with epididymal or testicular sperm with children conceived after ICSI with ejaculated sperm. Methods This retrospective study included 317 children born after ICSI with percutaneous epididymal sperm aspiration (PESA), 103 children born after ICSI with testicular sperm aspiration (TESA), and a control group of 1008 children born after ICSI with ejaculated sperm. All of the patients received their assisted reproductive treatment in the Reproductive Medicine Center of the First Affiliated Hospital of Zhengzhou University from January 2004 to December 2011. Data, such as the rate of stillbirths, perinatal mortality, gestational age, birth weight, and the rate of congenital malformations of the three groups, were compared. Results PESA and TESA children were not different from ICSI children in the rate of stillbirths, perinatal mortality, infant mortality rate, gestational age, the rate of prematurity, and the rate of malformations (P〉0.05). A slight increase in birth defects was reported in the TESA group compared with those in the control group, but there was no significant difference between the groups (P〉0.05). Conclusion ICSI with epididymal or testicutar sperm does not lead to more stillbirths or congenital malformations compared with ICSI using ejaculated sperm. Background To evaluate the safety of intracytoplasmic sperm injection (ICSI) with epididymal or testicular sperm, this study compared children born after ICSI treatment with epididymal or testicular sperm with children conceived after ICSI with ejaculated sperm. Methods This retrospective study included 317 children born after ICSI with percutaneous epididymal sperm aspiration (PESA), 103 children born after ICSI with testicular sperm aspiration (TESA), and a control group of 1008 children born after ICSI with ejaculated sperm. All of the patients received their assisted reproductive treatment in the Reproductive Medicine Center of the First Affiliated Hospital of Zhengzhou University from January 2004 to December 2011. Data, such as the rate of stillbirths, perinatal mortality, gestational age, birth weight, and the rate of congenital malformations of the three groups, were compared. Results PESA and TESA children were not different from ICSI children in the rate of stillbirths, perinatal mortality, infant mortality rate, gestational age, the rate of prematurity, and the rate of malformations (P〉0.05). A slight increase in birth defects was reported in the TESA group compared with those in the control group, but there was no significant difference between the groups (P〉0.05). Conclusion ICSI with epididymal or testicutar sperm does not lead to more stillbirths or congenital malformations compared with ICSI using ejaculated sperm.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2013年第11期2129-2133,共5页 中华医学杂志(英文版)
关键词 intracytoplasmic sperm injection epididymal spermatozoa testicular spermatozoa birth defects intracytoplasmic sperm injection epididymal spermatozoa testicular spermatozoa birth defects
  • 相关文献

参考文献28

  • 1Palermo G, Joris H, Devroey P, Van Steirteghem AC. Pregnancies after intracytoplasmic injection of single spermatozoom into an oocyte. Lancet 1992; 340: 17-18.
  • 2Glina S, Fragoso JB, Martins FG, Soares JB, Galuppo AG, Wonchockier R. Percutaneous epididymal sperm aspiration (PESA) in men with obstructive azoospermia. Int Braz J Urol 2003; 29: 141-146.
  • 3Gorgy A, Podsiadly BT, Bates S, Craft IL. Testicular sperm aspiration (TESA): the appropriate technique. Hum Reprod 1998; 13: 1111-1113.
  • 4Ludwig M,Katalinic A. Pregnancy course and health of children born after ICSI depending on parameters of male factor infertility. Hum Reprod 2003; 18: 351-357.
  • 5Wennerholm UB, Bergh C, Hamberger L, Westlander G, Wikland M, Wood M. Obstetric outcome of pregnancies following ICSI, classified according to sperm origin and quality. Hum Reprod 2000; 15: 1189-1194.
  • 6Kollan B, Finnstrom O, Lindam A, Nilsson E, Nygren KG, Otterblad PO. Congenital malformations in infants born after in vitro fertilization in Sweden. Birth Defects Res A Clin Mol Terato12010; 88: 137-143.
  • 7Woldringh GH, Besselink DE, Tillema AH, Hendriks JC, Kremer JA. Karyotyping, congenital anomalies and follow- up of children after intracytoplasmic sperm injection with non- ejaculated sperm: a systematic review. Hum Reprod Update 2010; 16: 12-19.
  • 8Belva F, De Schrijver F, Tournaye H, Liebaers I, Devroey P, Haentjens P, et al. Neonatal outcome of 724 children born after ICSI using non-ejaculated sperm. Hum Reprod 2011; 26:1752- 1758.
  • 9Sun YP, Xu Y, Cao T, Su YC, Guo YH. Zona pellucida thickness and clinical pregnancy outcome following in vitro fertilization. Int J Gynaecol Obstet 2005; 89: 258-262.
  • 10Woldringh GH, Horvers M, Janssen A J, Reuser J J, de Groot SA, Steiner K, et al. Follow-up of children born after ICSI with epididymal spermatozoa. Hum Reprod 2011; 26:1759-1767.

同被引文献38

引证文献5

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部