摘要
辣椒素受体(TRPVl)是机体一个重要的感受伤害性刺激的信号分子。近年来研究发现TRPVl在消化道分布广泛,并且参与了众多生理和病理过程,对胃肠黏膜屏障、胃肠动力、胃酸分泌的调节及在内脏高敏感形成中均有重要作用。TRPV1与消化功能的关系正在受到重视,本文对其作一综述。
The transient receptor potential type 1 ion channel （TRPV1） is an important signal molecular responding to the noxious stimuli. Recent studies have showed that the TRPV1 is widely distributed in the gastrointestinal tract, it participates in the regulation of gastrointestinal function such as the protection of the gastrointestinal mucosa, the regula tion of gastrointestinal motility and gastric acid secretion and plays an important role in visceral hypersensitivity. This arti cle aimed to make a view of the relationship between TRPV1 and digestive function
出处
《胃肠病学和肝病学杂志》
CAS
2013年第6期593-596,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
TRPV1
消化功能
辣椒素
胃肠黏膜
胃肠动力
胃酸分泌
内脏高敏感
TRPV1
Digestive function
Capsaicin
Gastrointestinal mucosa
Gastrointestinal motility
Gastric acidsecretion
Visceral hypersensitivity
