摘要
目的:评价18F-FDG PET/CT显像对结直肠癌患者术后复发与转移的诊断价值与PET/CT检查期间CEA水平之间的关系。方法:收集临床症状、血清CEA水平升高或CT等影像学检查怀疑复发,并因此行PET/CT检查的结直肠癌术后患者75例,其中男性46例,女性29例。回顾性分析比较PET/CT显像的诊断价值在结直肠癌术后患者CEA阳性组与阴性组中的差异。结果:PET/CT对复发与转移的检出率中CEA阳性组为89.3%(42/47),阴性组为82.1%(23/28),两组之间检出率差异无统计学意义(P>0.05)。结论:CEA水平无助于提高PET/CT对结直肠癌患者术后复发与转移的检出率,PET/CT对结直肠癌患者术后复发与转移具有较高的检出率,是目前监测结直肠癌患者术后复发与转移较为理想的方法。
Objective： This work aimed to evaluate the relationship of the diagnostic value of PET/CT in patients with postopera- tive recurrent and metastatic colorectal cancer （CRC）, as well as with different levels of carcino-embryonic antigen （CEA）, during PET/ CT scanning. Methods： Data of 75 patients （46 males and 29 females） with suspected recurrent and metastatic CRC were collected. The patients underwent PET/CT examination in Shanxi Provincial Tumor Hospital in Taiyuan. The differences of the PET/CT diagnos- tic values in CEA-positive and CEA-negative patients with recurrent CRC after surgery were retrospectively analyzed and compared. Results： Among the 75 CRC patients, 67 had recurrence and metastasis as confirmed by histopathological diagnosis or clinical fol- low-up data. By contrast, PET/CT examination results revealed 65 cases were true positive （a false positive foci was diagnosed in one of the patients）, 8 were true negative, and 2 were false negative. Correspondingly, the sensitivity and degree of accuracy were 97.0% and 96.0%, respectively. The detection rates of PET/CT for the recurrence and metastases were 89.3% in the CEA-positive group and 82.1% in the CEA-negative group. No significant differences were observed between the two groups. Conclusion： CEA levels do not help improve the detection rate of PET/CT in the recurrence and metastasis of CRC. PET/CT imaging has high sensitivity and degree of accuracy in detecting recurrence and metastasis after colon cancer surgery. Therefore, this method is ideal for monitoring relapsed and metastatic foci of postoperative colon cancer cases.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2013年第12期717-720,共4页
Chinese Journal of Clinical Oncology
关键词
结直肠癌
正电子发射计算机体层扫描
癌胚抗原
colorectal neoplasm, positron-emission tomography, carcino-embryonic antigen
