摘要
枸杞多糖是我国传统中药枸杞的主要有效成分,近年来药理研究发现枸杞多糖对生殖功能的保护作用,包括改善动物交配能力,提高精子的质量和数量,预防高热、H2O2和辐照等造成的睾丸和生精上皮损伤,能逆转半去势或辐照大鼠的睾丸激素下降等。本文主要综述枸杞多糖生殖保护作用及其机制的研究进展。
The main active component of the fruits of Lycium barbarum L. , a traditional Chinese medi- cine, is Lycium barbarum polysaccharides （LBP）. In recent years some studies have shown that LBP was benefi- cial to reproduction system in several aspects： the male copulatory performance was improved; the quality, quantity and motility of sperms were increased; the quality, quantity and motility of sperms were increased after LBP treat- ment; the damage of testis and seminiferous epithelium caused by different factors, such as hyperthermia, H2O2 and irradiation, were prevented by LBP; and lastly, the decrease in testosterone of hemi castrated or irradiated rats was reversed by LBP. This article reviewed the progress of the studies on the reproductive protection effects and mechanisms of lycium barbarum polysaccharides.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2013年第12期1421-1424,1451,共5页
Chinese Journal of New Drugs
基金
广西壮族自治区卫生厅中医药医院制剂类课题(GZYZ-10-05)
广西中医药管理局中医药科技专项课题(GZYZ1101)
关键词
枸杞多糖
生殖保护
作用机制
lycium barbarum polysaccharides
reproductive protection
mechanism
