摘要
目的:运用中医体质防治方案对高血压病血栓前状态(pro-thrombotic state,PTS)患者进行早期干预,观察血压病控制情况、患者生活质量、高血压血栓前状态分子标志物水平及心肌梗死与脑梗死发生率的影响,评价高血压血栓前状态的社区中医体质防治方案的可行性。方法:对240高血压病血栓前状态患者进行中医体质干预,并与西医治疗对照,随访1年后进行对比研究。结果:体质组血压控制情况体质组与对照组差异有统计学意义(P<0.05);体质组较对照组生活质量改善明显(P<0.05);体质组PTS分子标志物水平中vWF、GMP-140、11-DH-TXB2下降显著,AT升高显著,与对照组比较差异有统计学意义(P<0.05);心肌梗死率及脑梗死率,差异有统计学意义(P<0.05)。结论:高血压血栓前状态的社区中医体质防治方案的干预效果显著。
Objective: TCM constitution prevention scheme was used to make an early intervention of the prethrombotic state of hypertension patients(pro-thrombotic state,PTS) and to observe the impact of their blood pressure control,their life quality,their molecular marker levels of hypertension prethrombotic state on the incidence of myocardial infarction and cerebral infarction,and evaluate the feasibility of TCM constitution prevention scheme for the hypertension prethrombotic state.Methods: 240 patients were given with TCM constitution intervention and a control study with western medicine was made through one-year follow-up.Results: The blood pressure control in the constitution group had statistically significant difference(P < 0.05),compared with that of the control group.The life quality of the physical group obviously improved,compared with that of the control group.PTS molecular markers of vWF,GMP-140 and 11-DH-TXB2 of the constitution group significantly decreased and AT significantly increased,showing statistically significant difference(P < 0.05),compared with that of the control group.The difference of the myocardial infarction and cerebral infarction rate was statistically significant(P < 0.05).Conclusion: The intervention effect of the TCM constitution scheme for the prethrombotic state of the hypertension patients is significant.
出处
《云南中医中药杂志》
2013年第6期13-16,89,共4页
Yunnan Journal of Traditional Chinese Medicine and Materia Medica
基金
广西中医药管理局中医药科技专项课题合同编号:GZKZ10-001
关键词
高血压病血栓前状态
中医体质
早期干预
hypertension prethrombotic state,TCM constitution,early intervention
