摘要
巴斯德毕赤酵母是一种近年来广泛使用的基因表达系统 ,它具有表达率高、遗传稳定、产物可分泌、发酵工艺成熟等许多优点 .综述了该系统在载体类型、载体元件 (包括启动子、选择标记和信号肽序列 )、受体类型。
Pichia pastoris has been utilized widely as a heterologous gene expression system recently. There are several advantages such as high productivity , stable inherity, secretable product, and mature fermentation techniques. The advances of vector types, vector elements(including promoter, selection marker and signal sequence), host strains, and the strategy for increasing integration copy number were reviewed.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
2000年第2期151-154,共4页
Progress In Biochemistry and Biophysics
基金
国家自然科学基金资助项目!( 2 99760 13 )
