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肥胖和代谢综合征的药物治疗与研究进展 被引量：5

Research progress of the drug treatment of obesity and metabolic syndrome
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摘要 肥胖与IR被公认为是代谢综合征的重要致病因素,本文通过讨论肥胖和脂肪组织的关系综述了目前食欲抑制剂、消化吸收阻滞剂、降糖药物(双胍类、α-糖苷酶抑制剂、GLP-1和DPP-4抑制剂)和代谢刺激剂在肥胖药物治疗中的研究进展;同时又从脂代谢异常角度讨论了胰岛素增敏剂和调脂药物(他汀类、贝特类和烟酸)在代谢综合征的药物治疗中研究进展。最后结论为调脂药物的研究已获得广泛成效,但新的减肥药物的研发仍有待进一步突破。
作者 黄建权 王观春 由凯
机构地区 航天中心医院药剂科
出处 《药品评价》 CAS 2013年第9期25-32,共8页 Drug Evaluation
关键词 肥胖 代谢综合征 西布曲明 奥利司他 噻唑烷二酮 调脂药物
分类号 R589.2 [医药卫生—内分泌]
  • 相关文献

参考文献64

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共引文献686

同被引文献64

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引证文献5

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药品评价
2013年 第9期

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