摘要
[目的]了解本地区老年农民丙氨酸转氨酶(alanine aminotransferase,ALT)水平和乙型肝炎病毒感染状况,旨在为老年人ALT及乙型肝炎病毒表面抗原(HBsAg)提供参考区间及分布范围。[方法]回顾性分析本地区2012年8月至2012年12月4125例老年农民的ALT水平及HBsAg的检测结果,按年龄段将老年人分为5组,分别为60～64岁,65～69岁,70～74岁,75～79岁,≥80岁,再按性别进行分组,共10组。ALT采用速率法全自动生化仪检测,HBsAg采用酶标法检测。[结果]1 920例老年男性农民ALT水平为21(9～68)U.L-1,2 205例老年女性农民ALT水平为19(9～69)U.L-1,不同性别间ALT水平比较,差异有统计学意义(z=7.796,P<0.001);老年男性农民HBsAg阳性率为4.06%,老年女性农民HBsAg阳性率为3.45%,不同性别间HBsAg阳性率比较,差异无统计学意义(χ2=1.096,P=0.295)。[结论]乙型肝炎病毒感染状况特别是HBsAg阳性率,除在少数年龄段不同性别有差异外,大部分年龄段在不同性别间差异无统计学意义(P>0.05),但本地区老年农民不同性别、不同年龄段ALT水平差异很大,因此临床应根据不同年龄、性别建立不同的参考区间。
[Objective] To understand local senile peasants’alanine aminotransferase（ALT） and hepatitis B virus infection to offer reference interval and distri bution range for senile ALT and HBsAg.[Method]Trace back and analyse the examinations of local 4125 cases senile peasants’ALT level and hepatitis B virus HBsAg,divide them into 5 groups under ages,i.e.60～64,65～69,70～74,75～79 and ≥80 years old,then re-divide them into 10 groups under sex.Take velocity method and automatic biochemical analyzer to test ALT and enzyme linked immunosorbent assay to test HBsAg.[Result]1920 cases of se nile male peasants’ ALT level is 21（9～68）U.L-1,2 205 female peasants’ALT is 19（9～69）U.L-1;by comparison,their difference has statistical meaning（z= 7.796,P＆lt;0.001）;senile male peasants’HBsAg positive rate is 4.06%,and 3.45% for female,the comparison of them has no statistical meaning（X2=1.096,P= 0.295）.[Conclusion]The hepatitis B virus infection,esp.HBsAg positive rate,except for difference of ages,most part of them has no difference of statistical meaning for both sexes;however,there’s big difference on ALT level in different sex and ages and sexes;so in clinic,we shall set up different reference ranges under different age and sex.
出处
《浙江中医药大学学报》
CAS
2013年第6期737-739,共3页
Journal of Zhejiang Chinese Medical University
