摘要
目的比较两种不同超滤方法对成人心脏直视手术库血用量的影响。方法 100例成人心脏直视手术患者随机分为两组,零平衡超滤组(A组)和零平衡超滤+改良超滤组(B组),每组50例。两组在体外循环(ECC)开始后均进行零平衡超滤,ECC结束后A组停止超滤,而B组继续进行改良超滤10～12min,流量10～15mL/(kg.min)。观察两组患者血红蛋白(Hb)在术前、术中、停机、关胸时的变化,对比两组患者库血的用量。结果两组患者在年龄、体重及体外循环时间上差异均无统计学意义(均P>0.05);Hb水平在术前、术中、停机时差异无统计学意义,而关胸时B组明显高于A组(P<0.05);库血用量B组低于A组,差异有统计学意义(P<0.05)。结论成人心脏直视手术中应用零平衡超滤+改良超滤可以迅速提高患者术后Hb水平,明显减少临床库血用量。
Objective To investigate the effect of two different techniques of ultrafiltration on the stored blood transfusion in adult open heart surgery.Methods A total of 100 adult patients who underwent open heart surgery were randomly divided into two groups：zero-balanced ultrafiltration group（group A,n=50）and zero-balanced plus modified ultrafiltration group（group B,n=50）.Zero-balanced ultrafiltration was initiated after extracorporeal circulation（ECC）in both groups.After cessation of ECC,ultrafiltration was stopped in group A,while modified ultrafiltration was performed for 10—12min at a flow of 10—15mL/（kg.min）in group B.Hemoglobin（Hb）at the time of preoperation,intra-operation,cessation of ECC and closure of the chest was detected in both groups.The volume of stored blood transfusion was compared between the two groups.Results There was no significant difference in preoperative clinical data and ECC time between the two groups（P〉0.05）.The content of Hb at the time of closure of the chest was evidently higher in group B than in group A（P〈0.05）.The patients in group B required less stored blood transfusion than those in group A（P〈0.05）.Conclusion Application of zero-balanced ultrafiltration plus modified ultrafiltration in open heart surgery helps increase postoperative Hb and reduce the volume of stored blood transfusion.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2013年第3期321-323,共3页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
关键词
超滤
体外循环
库血用量
ultrafiltration
extracorporeal circulation
volume of blood transfusion
