摘要
目的探讨颈动脉内中膜厚度(IMT)、斑块指数及血清高敏C-反应蛋白(hs-CRP)浓度等指标与冠脉病变程度的关系,从而对冠心病的早期预防提供新的途径。方法对1 506例患者进行冠脉造影,颈动脉彩超及血清hs-CRP检查。根据造影结果分为对照组(814例),单支病变组(341例),双支病变组(131例)和三支病变组(220例),检测IMT、hs-CRP及计算斑块指数。结果对照组IMT、斑块指数及hs-CRP与冠心病组差异均有统计学意义。单支病变组IMT及斑块指数与双支病变组及三支病变组差异有统计学意义,而双支病变组及三支病变组组间差异无统计学意义。hs-CRP在冠心病组间差异无统计学意义。结论通过彩超检测颈动脉IMT和斑块指数及测定血清hs-CRP浓度对冠心病的早期诊断,治疗及观察其疗效有重要的临床价值。
Objective To investigate the relationship among the degree of coronary artery disease and the intima-media thickness（IMT）and plaque index of carotid and serum levels of high sensitivity C-reactive protein（hs-CRP）,and provide a new way to early prevention of coronary heart disease.Methods Totally 1506 cases received coronary angiography,carotid ultrasound and detection of serum C-reactive protein.According to the results of coronary angiography,the patients were divided into control group（814）,single-vessel disease group（314）,two-vessel disease group（131）,three-vessel disease group（220）.The IMT,plaque index and hs-CRP were detected for all subjects.Results The control group＇s IMT,plaque index and hs-CRP had significant difference to coronary heart disease（CHD）group.The single-vessel disease group＇s IMT and plaque index had significant difference to the other two group of CHD,but the two-vessel disease group and three lesions had no significant differences.The levels of Hs-CRP in different group with coronary heart disease had no significant differences.Conclusion IMT,plaque index and hs-CRP have important clinical value for the early diagnosis,treatment and evaluation the effect of coronary heart disease.
出处
《中国煤炭工业医学杂志》
2013年第7期1063-1065,共3页
Chinese Journal of Coal Industry Medicine
