摘要
目的探讨痰热清注射液与头孢呋辛联合应用治疗急性上呼吸道感染的临床效果,为临床治疗提供参考。方法选取医院2010年5月-2012年5月收治的急性上呼吸道感染患者120例,采用随机数字表法分为对照组和联合治疗组,每组各60例;其中对照组采用头孢呋辛钠静脉滴注治疗;联合治疗组在对照组治疗基础上加用痰热清注射液静脉滴注治疗;比较两组患者临床治疗总有效率、临床症状、体征改善时间及咽拭子培养阳性率等的差异。结果患者临床治疗总有效率联合治疗组为91.7%,对照组为78.3%,差异有统计学意义(P<0.05);患者退热时间联合治疗组为(2.0±0.6)d,对照组为(4.3±1.5)d,差异有统计学意义(P<0.05);患者咳嗽消失时间联合治疗组为(3.3±1.0)d,对照组为(4.6±1.7)d,差异有统计学意义(P<0.05);患者咽痛消失时间联合治疗组为(3.5±0.9)d,对照组为(5.0±1.5)d,差异有统计学意义(P<0.05);患者咽部充血消失时间联合治疗组为(3.7±1.1)d,对照组为(5.4±1.8)d,差异有统计学意义(P<0.05);患者咽拭子培养阳性率联合治疗组为1.7%,对照组的10.0%,差异有统计学意义(P<0.05)。结论痰热清注射液与头孢呋辛联合应用治疗急性上呼吸道感染能够有效改善临床症状和体征,缩短病程,具有临床应用价值。
OBJECTIVE To investigate the therapeutic effect of Tanreqing injection combined with cefuroxime on treatment of acute upper respiratory tract infections so as to guide the clinical treatment.METHODS A total of 120 patients with acute upper respiratory tract infections,who were treated in the hospital from May 2010to May 2012,were enrolled in the study and were randomly divided into the control group and the treatment group with 60 cases in each group.The control group was treated with cefuroxime intravenous injection,and the treatment group was treated with Tanreqing injection intravenous injection on the basis of treatment of the control group,then the total effective rate of clinical treatment,the clinical symptoms,time of sign improvement,and the positive rate of throat swab culture were compared between the two groups.RESULTS The total effective rate of clinical treatment in the combined treatment group was 91.7%,significantly higher than 78.3%of the control group,the difference was statistically significant（P〈0.05）.The time of fever disappearance of the combined treatment group was（2.0 ±0.6）days,significantly shorter than（4.3±1.5）days of the control group,the difference was statistically significant（P〈0.05）;the time of cough disappearance of the combined treatment group was（3.3±1.0）days,significantly shorter than（4.6±1.7）days of the control group,the difference was statistically significant（P〈0.05）;the time of throat sore disappearance of the combined treatment group was（3.5±0.9）days,significantly shorter than（5.0±1.5）d of the control group,the difference was statistically significant（P〈0.05）;the time of throat congestion disappearance of the combined treatment group was（3.7±1.1）days,significantly shorter than（5.4±1.8） days of the control group,the difference was statistically significant（P〈0.05）;the positive rate of throat swab culture of the combined treatment group was 1.7%,significantly lower than 10.0%of the control group,the difference was statistically significant（P〈0.05）.CONCLUSION Tanreqing injection combined with cefuroxime,as is used for the treatment of acute upper respiratory tract infections,can efficiently improve the clinical symptoms and signs and shorten the disease course,and it is worthy of clinical application.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第13期3230-3232,共3页
Chinese Journal of Nosocomiology
关键词
痰热清注射液
头孢呋辛
急性上呼吸道感染
Tanreqing injection
Cefuroxime
Acute upper respiratory tract infection
