摘要
介绍了β-环糊精的基本性质,综述了β-环糊精及其衍生物作为流动相添加剂在高效液相色谱和高效毛细管电泳手性分离中的应用,并探讨了其作为手性流动相添加剂的特点.指出β-环糊精是良好的手性识别体,不仅可作为色谱手性固定相,还可作为流动相添加剂,用于手性对映体的拆分.
A review is provided of the basic properties ofβ-cyclodextrin as well as the applica- tion of β-cyclodextrin and its derivatives as mobile phase additives for chiral separation with high performance liquid phase chromatography and high performance capillary electrophoresis. The features of β-cyclodextrin and its derivatives as chiral mobile phases are discussed. It is pointed out that, an excellent chiral recognition ionophore, β-cyclodextrin can be used as both chromatography chiral stationary phase and mobile phase additive for the separation of chiral enantlomers.
出处
《化学研究》
CAS
2013年第1期97-103,共7页
Chemical Research
基金
云南省科技厅资助项目(2011FZ043)
昆明理工大学分析测试基金资助项目(2011453)
关键词
Β-环糊精
流动相添加剂
手性分离
应用
综述
β-cyclodextrin
mobile phase additive
chiral separation
application
review
