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胰腺疾病的诊疗进展(摘译) 被引量:2

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摘要 胰腺癌的早期诊断:挑战和新进展 Early diagnosis of pancreatic cancer:challenges and new developments [J].[美国]Kaur S,Baine MJ,Jain M,et al.Biomark Med,2012,6(5):597-612. 胰腺癌是致命的恶性肿瘤,其发病率几乎与病死率相等.有效治疗胰腺癌的主要困难是:复杂的生理病理学、缺少早期诊断和预后标志物、放疗和化疗效果不显著.治疗药物效果较差(即使是在浸润性肿瘤的早期阶段),更加强调了早期诊断胰腺癌的重要性.本综述探讨了用于早期检测胰腺癌的肿瘤标志物的研究进展,包括血清标志物、循环肿瘤细胞、自身免疫抗体、外遗传标志物和miRNA.考虑到恶性病变与原发性和转移性胰腺癌之间较长的时间间隔,研发潜在有效的诊断和预后标志物是非常有可能的.
作者 谷俊朝
出处 《国际外科学杂志》 2013年第6期412-413,共2页 International Journal of Surgery
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