摘要
探讨人血丙种球蛋白 ( IVIG)治疗特发性血小板减少性紫癜 ( ITP)的疗效 ,并与激素治疗进行比较。方法 :将明确诊断的 57例 ITP分为丙球治疗组、丙球加激素组、激素组 ,观察第 1～ 7天血小板变化情况。结果 :3组治疗均有效 ,但起效时间 IVIG组及混合组优于激素组。3 d内血小板上升率 IVIG组 4 4 % ,混合组 50 % ,激素组 1 0 % ,经χ2 检验 ,IVIG组与混合组比较无显著差异 ( P>0 .0 5) ,而分别与激素组比较 ,均有显著差异 ( P<0 .0 5)。结论 :IVIG治疗ITP起效快 ,控制出血症状明显 ,优于激素治疗。
Objective:To investigate the effect of Human gamma globulin on teating ITP and compare the difference between Human gamma globulin and hormone.Methods:57 cases of ITP were divided into three groups, one teated with Human gamma globulin,(IVIGG), the another with both human gamma globulin and hormone (MG), the third with only hormone (HG). The changes of platelet count were observed during the 7 days after treatment.Results:During the first three days,the rate of platelet count improvment in IVIGG,MG and HG were 44%,50% and 10%, respectively. A significant difference between IVIGG and HG, and also MG and HG was found(P<0.05).Conclusion:To treat ITP, the IVIG showed a fast effect and was easy to control the hemorrhage. So IVIG is belived to be a better therapy than that of hormonetherapy.
出处
《华夏医学》
2000年第2期131-132,共2页
Acta Medicinae Sinica
关键词
丙种球蛋白
激素
血小板
紫癜
human gamma globulin
hormone
platelet
ITP
