摘要
目的探讨第13组淋巴结是否可作为前哨淋巴结预测壶腹周围癌淋巴结转移情况。方法选择2009年1月至2012年1月中国医学科学院肿瘤医院77例行Whipple术的壶腹周围癌。其中26例（试验组，男18例、女8例，年龄38～79岁）行Whipple术中，采用1％亚甲蓝或纳米碳混悬液术中瘤床注射，另外51例作为对照组不注射，其中男33例、女18例，年龄33—78岁。对染色的第13组淋巴结进行活检，之后常规行淋巴结清扫术，并对淋巴结转移情况进行研究。结果试验组患者在瘤床注射1％亚甲蓝或纳米碳混悬液能够显示出肿瘤淋巴结的引流范围；对照组和试验组患者平均清扫淋巴结个数分别为15．8（3—54）个和17．6（6～40）个，差异无统计学意义（P=0．460）。结论第13组淋巴结可能并不适合作为前哨淋巴结用于预测胰腺及壶腹周围癌淋巴结转移情况。
Objective To study the feasibility and clinical value of 13th lymph nodes in predicting general lymph nodes metastases for periampullary carcinoma. Methods A total of 77 patients with pathologically confirmed periampullary carcinoma were recruited. And 26 （ 18 males and 8 females, age 38 -79 years） of them underwent Whipple procedures during which 1% methylene blue or nanogate carbon was injected into tumor bed. The othor 51 patients as controls （33 males, 18 females, age 38 -78 years）. The dyed 13th lymph nodes were biopsied. Then routine lymphadenectomy was performed and their pathological results were analyzed. Results In the experimental group, the lymph node drainage area of cancer was identified. However, in contrast with 51 patients in the control group, the labeling of 13th lymph nodes did not significantly increase the number of cleaned lymph nodes （ 15.8 （3 -54） vs 17. 6 （6 -40 ）, P = 0. 460）. Conclusion 13th lymph nodes are non-suitable as sentinels for predicting general lymph nodes metastases of periampullarv carcinoma.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2013年第24期1900-1902,共3页
National Medical Journal of China
关键词
肝胰管壶腹
淋巴结
壶腹周围癌
Ampulla of vater
Lymph nodes
Periampullary carcinoma
