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热疗联合复方苦参注射液改善晚期癌痛患者生存质量的临床研究 被引量:6

Clinical Research of Hyperthermia Combined with Matrine Compound Injections in Improving the Life Quality of Patients with Terminal Cancer Pain
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摘要 目的观察热疗联合复方苦参注射液改善晚期癌痛患者生存质量的临床疗效。方法将晚期癌痛患者60例随机分为治疗组和对照组。治疗组30例采用热疗联合复方苦参注射液治疗,对照组30例单用复方苦参注射液治疗。观察两组患者治疗前后生存质量、止痛效果的变化。结果治疗组、对照组的卡氏评分均较治疗前明显提高,治疗组提高尤为显著,二组比较差异有统计学意义(P<0.05)。两组间生存质量评分治疗前差异无统计学意义(P>0.05),治疗后两组均有显著性改善(P<0.05),且治疗组症状改善明显优于对照组(P<0.05)。治疗组止痛总有效率达70%,对照组总有效率为60%,二组均有一定的止痛效果,两组比较差异无统计学意义(P>0.05)。结论热疗联合复方苦参注射液能有效地提高晚期癌症患者的生活质量,并且在控制肿瘤进展方面也有一定的作用。 Objective To observe the clinical efficacy of hyperthermia combined with matrine compound injec- tion in improving the life quality of patients with terminal cancer pain. Methods Sixty patients with terminal canc- er pain were divided into the treatment group and the control group. The treatment group of 30 patients was given hyperthermia combined with matrine compound injection. The control group of 30 patients was administered only matrine compound injection. Karnofsky score,quality of life score,the analgesic effect were observed both before and after the treatment. Results Karnofsky score and the quality of life in the treatment group and the control group were both significantly increased after the treatment(P〈0.05), with more obvious increase in the treatment group than that in the control group(P〈0.05). The total analgesic effective rate of the treatment group was 70%, whereas 60% in the control group,without significant difference between two groups(P〉0.05). Conclusion Hy- perthermia combined with matrine compound injection can effectively improve the life quality of patients with ter- minal cancer pain, and also have a role in the control of tumor progression.
出处 《中西医结合研究》 2013年第3期125-127,132,共4页 Research of Integrated Traditional Chinese and Western Medicine
关键词 热疗 复方苦参注射液 晚期癌症 生存质量 hyperthermia matrine compound injection terminal cancer pain quality of life
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