摘要
目的探讨椎动脉优势在后循环缺血性眩晕(VAIV)中的临床意义。方法前瞻性收集经头颅MRA检查发现的椎动脉优势的VAIV患者41例为研究对象,以非椎动脉优势的患者36例为对照,比较两组患者的基底动脉情况及眩晕严重程度。将椎动脉优势组患者根据椎动脉直径差异分为轻度变异组(0.04～0.70mm)、中度变异组(0.70～1.17mm)、重度变异组(≥1.17mm)3组,比较3组患者的眩晕严重程度差异。所有患者均随访1年,观察椎动脉优势与阳性事件发生(眩晕反复发作或发生后循环脑梗死)的关系。结果 (1)椎动脉优势组基底动脉形状异常率为70.73%(29/41),明显高于非椎动脉优势组33.33%(12/36)(χ2=10.77,P<0.01);(2)椎动脉优势组眩晕严重程度(3.3±1.2)高于非椎动脉优势组(2.3±0.6)(t=1.99,P<0.01);不同变异3组间两两比较,椎动脉优势重度变异组眩晕严重程度(4.0±1.1)大于轻度变异组(2.9±0.9)(t=2.07,P<0.05);(3)随访1年后,椎动脉优势组阳性事件发生率(65.85%)高于非优势组(30.56%)(χ2=9.56,P<0.01)。结论椎动脉优势的VAIV患者基底动脉异常率高,眩晕程度更严重,更容易反复发作眩晕或发生后循环脑梗死。
Objective To investigate the clinical significance of vertebral artery dominance in vertebrobasilar arterial insufficiency vertigo（VAIV）. Methods Forty-one vertigo patients with vertebral artery dominance detected by head magnetic resonance angiography（MRA） were included prospectively as the study group,and thirty-six vertigo patients without vertebral artery dominance were recruited as the control group.The shape of basilar artery and the severity of vertigo in the two groups were compared.The vertebral artery dominance group was divided into three subgroups according to their vertebral arteries diameter difference： the mild variation subgroup（0.04-0.70 mm）,the moderate variation subgroup（0.70-1.17 mm） and the severe variation subgroup（≥1.17 mm）.All the patients were followed up for one year,the relationship between the occurrence of vertigo event（recurrent attacks of vertigo or suffer infarction in vertebral-basilar artery system） and vertebral artery dominance were analyzed. Results （1） The abnormal rate of basilar artery was 70.73%（29/41）in the vertebral artery dominance group,which was significantly higher than 33.33%（12/36）（χ2 =10.77,P0.01） in the vertebral artery non-dominance group;（2）There was statistically difference in the severity of vertigo between the vertebral artery dominant group and the vertebral artery non-dominant group（3.3±1.2 vs 2.3±0.6）（t=1.99,P0.01）.There was also statistically difference in the severity of vertigo between the severe variation subgroup and the mild variation subgroup（4.0±1.1 vs 2.9±0.9）,（t=2.07,P0.05）;（3）After one year follow-up,the incidence of vertigo event in the vertebral artery dominance group（65.85%） was higher than that in the vertebral artery non-dominance group（30.56%）（χ2 =9.56,P0.01）. Conclusions The abnormal rate of basilar artery shape was higher in vertebral artery dominance vertigo;the more severe of the variation,the more common of recurrent vertigo attacks and infarction in vertebral-basilar artery system.
出处
《中国神经免疫学和神经病学杂志》
CAS
北大核心
2013年第4期253-255,259,共4页
Chinese Journal of Neuroimmunology and Neurology
关键词
后循环缺血性眩晕
椎动脉优势
基底动脉异常
vertebrobasilar arterial insufficiency vertigo
vertebral artery dominance
abnormal of basilar artery
