摘要
目的:比较地佐辛与吗啡对晚期癌痛患者的临床效果。方法:选择晚期癌痛患者86例,随机分为地佐辛组与吗啡组,每组43例,地佐辛组采用地佐辛注射液治疗,吗啡组采用盐酸吗啡注射液治疗,分别对两组患者的治疗效果和不良反应发生情况进行比较分析。结果:地佐辛组患者的显效率、有效率、总有效率均有所提高,无效率则有所降低,两组间比较差异无统计学意义(P>0.05);地佐辛组患者不良反应发生率为11.63%,显著低于吗啡组的32.56%,差异有统计学意义(P<0.05)。结论:地佐辛比吗啡更能够有效控制癌症患者的晚期疼痛,且不良反应发生率相对较低,适于临床借鉴和进一步应用。
Objective To probe into the clinical comparative analysis of dezocine and morphine treatment of advanced cancer.Methods Selected 86 advanced cancer patients in our hospital.The patients were divided into dezocine group（43 cases） and morphine group（43 cases） randomly.The patients in dezocine group were treated with dezocine injection.The patients in morphine group were treated with morphine hydrochloride injection.The clinical effect and adverse events of the patients in two groups with advanced cancer were compared and analysis. Results Compared with morphine group,the patients in dezocine group the rates of markedly effective,efficient and total effective were increased,and the rate of inefficiency decreased,but there were no significant difference（P〉0.05）.Compared with morphine group adverse reaction rate was 32.56%,the patients in dezocine group the adverse reaction rate was 11.63% reduce significantly, there were significant difference（P〈0.05）.Conelusion Compared with morphine,dezocine has effective effect to control the pain of patients with advanced cancer, and the incidence of adverse reactions was reduced relatively.lt is suitable for clinical reference and further applications.
出处
《吉林医学》
CAS
2013年第21期4205-4206,共2页
Jilin Medical Journal
关键词
地佐辛
吗啡
晚期癌痛
Dezocine
Morphine
Advanced cancer
