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肺癌与血栓栓塞关系的研究进展 被引量：11

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摘要 静脉血栓栓塞症（venous thromboembolism,VTE）包括肺血栓栓塞（pulmonary embolism，PE）、深静脉栓塞（deep venous thrombosis，DVT）和游走性栓塞性浅静脉炎，是肿瘤发展自然病程及抗肿瘤治疗过程中的常见并发症。流行病学资料表明肿瘤患者VTE发生率比非肿瘤患者高2～4倍^[1]。在各种肿瘤类型中，肺癌并发VTE几率较高，Blom等^[2]研究表明肺癌患者发生VTE的风险比非肿瘤病人高20倍。大约3％的肺癌患者在肿瘤诊断后的1年内发生VTE^[3]。
作者 谢灵敏 韩锋锋
机构地区 上海交通大学医学院附属新华医院呼吸科
出处 《中国呼吸与危重监护杂志》 CAS 2013年第4期430-432,共3页 Chinese Journal of Respiratory and Critical Care Medicine
关键词 静脉血栓栓塞症 肺癌患者 常见并发症 非肿瘤患者 流行病学资料 肺血栓栓塞 深静脉栓塞 抗肿瘤治疗
分类号 R734.2 [医药卫生—肿瘤]
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参考文献28

  • 1Heit JA, Silverstein MD, Mohr DN, et al. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case?control study. Arch Intern Med,2000,160:809-815.
  • 2Blom JW, Osanto S, Rosendaal FR. The risk of a venous thrombotic event in lung cancer patients: higher risk for adenocarcinoma than squamous cell carcinoma. J Thromb Haemost,2004,2: 1760-1765.
  • 3Chew HK, Davies AM, Wun T, et al. The incidence of venous thromboembolism among patients with primary lung cancer. J Thromb Haemost, 2008 ,6 : 601.Q08.
  • 4Shinagare AB, Guo M, Hatabu H, et al. Incidence of pulmonary embolism in oncologic outpatients at a tertiary cancer center. Cancer,2011,117:3860-3866.
  • 5Tagalakis Y, Levi D, Agulnik JS, et al. High risk of deep vein thrombosis in patients with non-small cell lung cancer: a cohort study of 493 patients. J Thorac Oncol ,2007 ,2: 729-734.
  • 6Hicks LK, Cheung MC, Ding K, et al. Venous thromboembolism and nonsmall cell lung cancer: a pooled analysis of National Cancer Institute of Canada. Cancer, 2009,115 :5516-5525.
  • 7Sorensen HT, Mellemkjaer L, Olsen JH, et al. Prognosis of cancers associated with venous thromboembolism. N Engl J Med, 2000 ,343 : 1846-1850.
  • 8Chuang YM, Y u CJ. Clinical characteristics and outcomes of lung cancer with pulmonary embolism. Oncology ,2009,77 : 100-106.
  • 9Lee JW, Cha SI, Jung CY, et al. Clinical course of pulmonary embolism in lung cancer patients. Respiration ,2009,78 :4248.
  • 10Malgor RD, Bilfinger TV, Labropoulos N. A Systematic review of pulmonary embolism in patients with lung cancer. Ann Thorac Surg, 2012,94:311-316.

同被引文献109

  • 1罗梅金,陈超英,赵景胜,丁文信,吴红花,徐朝久.肺癌患者发生VTE的临床特点、相关危险因素和预后分析[J].深圳中西医结合杂志,2022,32(20):12-16. 被引量：2
  • 2陈文慧,张予辉,王辰.恶性肿瘤与血液系统[J].国际呼吸杂志,2007,27(8):588-590. 被引量：11
  • 3孙建立,刘嘉湘,徐蔚杰.原发性支气管肺癌中医证的特征研究[J].中国中医基础医学杂志,2007,13(7):536-537. 被引量：42
  • 4Konstantinides SV, Torbieki A, Agnelli G, et al. 2014 ESC guidelines on the diagnosis and management of acute pul- monary embolism[J]. Eur Heart J, 2014,35 (43) : 3033- 3069.
  • 5Kearon C, Akl EA, Comerota AJ, et al. Antithrombotic therapy for VTE disease:antithrombotic therapy and pre- vention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines[J]. Chest, 2012,141 (2 Suppl) : 419-494.
  • 6Hicks LK,Cheung MC,Ding K,et al.Venous thromboembolism and nonsmall cell lung cancer:a pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials[J].Cancer,2009,115(23):5516-5525.
  • 7Haddad TC,Greeno EW.Chemotherapy-induced thrombosis[J].Thromb Res,2006,118(5):555-568.
  • 8Spyropoulos AC,Hussein M,Lin J,et al.Rates of venous thromboem-bolism occurrence in medical patients among the insured population[J].Thromb Haemost,2009,102(5):951-957.
  • 9Akl EA,Kamath G,Kim SY,et al.Oral anticoagulation may prolong survival of a subgroup of patients with cancer:a cochrane systematic review[J].J Exp Clin Cancer Res,2007,26(2):175-184.
  • 10Agnelli G,Gussoni G,Bianchini C,et al.Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or lo-cally advanced solid cancer receiving chemotherapy:a randomised,pla-cebo-controlled,double-blind study[J].Lancet Oncol,2009,10(10):943-949.

引证文献11

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中国呼吸与危重监护杂志
2013年 第4期

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