摘要
目的探讨不同的分娩方式和胶原蛋白特异性代谢产物吡啶酚与产后压力性尿失禁的相关性。方法选取2011年1月-2012年1月在广州市红十字会医院行产前检查、分娩并分娩后复查的产妇82例作为研究对象,根据不同的分娩方式分为阴道分娩组42例,选择性剖宫产组40例,比较两组产妇产后压力性尿失禁发生情况,并分析其相关因素,使用酶联免疫吸附试验法(ELISA)测定尿吡啶酚的浓度。结果①产后6～8周压力性尿失禁的总发生率为15.9%(13/82),其中阴道分娩组为26.2%(11/42),选择性剖宫产组为5.0%(2/40),阴道分娩组产后6～8周压力性尿失禁发生率高于选择性剖宫产组,差异有统计学意义(P<0.05)。②孕期发生尿失禁、分娩方式及新生儿体重是产后发生压力性尿失禁的主要影响因素(P<0.05)。③产后6～8周尿吡啶酚/肌酐值:阴道分娩组为(24.61±2.27)nmol/mmol,选择性剖宫产组为(22.11±3.55)nmol/mmol,阴道分娩组高于选择性剖宫产组,差异有统计学意义(P<0.05)。结论经阴道分娩的产妇产后压力性尿失禁的发生率及尿吡啶酚的浓度较选择性剖宫产产妇高。
Objective To explore the relevance between different delivery ways,collagen protein specificity metabolites of pyridinoline and postpartum stress urinary incontinence（SUI）.Methods 82 pregnant women who had antenatal examination,delivery and reexamine in Guangzhou Red Cross Hospital Affiliated to Medical College of Ji＇nan University from January 2011 to January 2012 were selected as research objects.According to the different ways of delivery,they were divided into two groups： vaginal delivery group（42 cases） and selective caesarean section group（40 cases）.Inci dence of SUI and the its relevant factors were compared and analyzed.The urinary pyridinoline concentration was measured by ELISA.Results ①6-8 weeks after delivery,the overall incidence of postpartum stress urinary inconti nence was 15.9%（13/82）,which were 26.2%（11/42） and 5.0%（2/40） in the vaginal delivery group and elective cae sarean section group respectively.Incidence of postpartum stress urinary incontinence in the vaginal delivery group was significantly higher than that in the selective caesarean section group,with statistically significant difference（P 0.05）.②Pregnancy urinary incontinence,delivery mode and neonatal birth weight were the main influence factors of postpartum stress urinary incontinence（P 0.05）.③6-8 weeks after delivery,urinary pyridinoline/Crin the vaginal delivery group was（24.61±2.27） nmol/mmol,which was significantly higher than（22.11±3.55） nmol/mmol in the selective caesarean section group,with statistically significant difference（P 0.05）.Conclusion Women with vaginal delivery have higher incidence of postpartum stress urinary incontinence and concentration of pyridinoline than those with selective caesarean section.
出处
《中国医药导报》
CAS
2013年第22期33-35,38,共4页
China Medical Herald
基金
广东省广州市卫生局科技项目(编号2009-YB-208)
关键词
压力性尿失禁
分娩方式
胶原代谢
尿吡啶酚
Stress urinary incontinence
Delivery way
Collagen metabolism
Urine pyridinoline
