摘要
目的:探讨烟酒刺激与口腔扁平苔藓(OLP)糜烂症状急性发作之间的关系。方法:根据是否吸烟、饮酒,分为吸烟暴露组(只吸烟不饮酒,共138人)、饮酒暴露组(只饮酒不吸烟,共110人)、烟加酒暴露组(既吸烟又饮酒,共77人)和非暴露组(不吸烟不饮酒)。各暴露组与非暴露组1:1配对。分别对各组暴露情况与糜烂发作情况进行相关性研究。结果:①吸烟暴露组糜烂发作的发生率与发作频率较非暴露组显著升高(P<0.01)。②饮酒暴露组糜烂发作的发生率与发作频率增高,较非暴露组有统计学差异(P<0.05)。③烟加酒暴露组糜烂发作的发生率显著高于非暴露组(P<0.01),发作频率较非暴露组有统计学差异(P<0.05)。④随着烟、酒摄入量的增加,OLP患者中糜烂症状急性发作的风险显著增高(P<0.01)。结论:吸烟、饮酒是导致OLP糜烂症状急性发作的危险因素。
Objective：To discuss the impact of smoking and alcohol drinking on acute erosive OLP.Method：OLP patients have been divided into 3 groups：smoking group,alcohol drinking group,smoking and alcohol drinking.The impact of exposure factors such as smoking and drinking on acute erosive OLP was investigated by the prospective epidemiological approach：the effect of exposure factors on the attack and frequency of acute erosive OLP was illustrated,i.e.,dose-response function and group differences between smoking and alcohol drinking.Result：①Compared to non-smoking patients with OLP,smoker with OLP of erosive occurrences attractions were higher than non-smoking ones（P 0.01）.②Compared to nondrinking patients with OLP,the alcohol drinker with OLP of erosive occurrences attractions were higher than no alcohol ones（P 0.05）.③Compared to no alcohol and tobacco patients with OLP,the OLP patients with alcohol and tobacco attack frequency was significantly higher（P 0.01）.④The amount of smoking,alcohol drinking stimulation and the erosion symptoms of acute exacerbation in OLP patients were significantly related（P 0.01）.Conclusion：There is a significant relationship between the stimulation of smoking or alcohol drinking and the incidence of OLP erosive attack or seizure frequency.
出处
《临床口腔医学杂志》
2013年第7期387-391,共5页
Journal of Clinical Stomatology
基金
国家中医药局"十一五"重点专病项目(09J1X1L420B227)
上海市科委基金(10DZ1974200
11DZ1972600)
上海市重点学科计划(S30206)
关键词
口腔扁平苔藓
糜烂
急性发作
吸烟
饮酒
危险因素
Oral lichen planus
erosive
acute
smoking
alcohol drinking
risk factors
