摘要
目的:探讨精索封闭治疗急性附睾炎的临床疗效。方法:120例急性附睾炎患者分为治疗组和对照组,并对其疗效进行回顾性对照分析。治疗组56例,年龄18～78(38.4±9.6)岁,使用2%利多卡因10 ml、庆大霉素(8万U)或阿米卡星(0.2 g)、地塞米松(5 mg)混合药物进行精索封闭,1次/d,必要时2次/d,5 d/疗程,两疗程间隔3～5 d。对照组64例,年龄14～82(41.3±7.2)岁,静滴青霉素钠640万U,1次/d,链霉素0.5 g肌注,2次/d,同时,口服复方新诺明,2片/d,2次/d,首次加倍;必要时换阿米卡星静滴,2次/d,口服药物不变。治疗时间均不超过2周。结果:治疗组治愈率为53.6%,显效率+有效率为37.5%,总有效率为91.1%,有效病例治疗时间为(9.2±0.5)d;对照组治愈率为40.6%,显效率+有效率为31.2%,总有效率为71.8%,有效病例治疗时间为(12.8±0.7)d。两组总有效率和有效病例治疗时间有显著性差异(P均<0.05)。结论:精索封闭治疗急性附睾炎操作简单,耐受性好,安全有效,疗程短,能在基层推广。
Objective ： To investigate the clinical effect of spermatic cord seal-up injection on acute epididymitis and its mecha- nisms. Methods ： A total of 120 cases of acute epididymitis were allocated to a trial group （ n = 56）, aged 18 - 7g （38.4 ± 9.6） years, and a control group （n =64）, aged 14 -82 （41.3 ±7.2） years. The patients in the trial group were given seal-up injections of a mixture of lidocaine, gentamicin （or Amikacin） and dexamethasone into the spermatic cord, qd or bid, for 2 courses of 5 days each, with an interval of 3 to 5 days. Those in the control group were treated by intravenous drip of penicillin, qd, intramuscular injection of Streptomycin, bid, and oral medication of SMZCo （ SMZ-TMP）, bid, with the initial dose doubled. After less than 2 weeks of treat- ment, we compared the therapeutic effects between the two groups of patients. Results： In the trial group, 53.6% of the patients were basically cured, 37.5% obviously improved and 91.1% improved （ total rate of effectiveness）. The average treatment time for the improved cases was （9.2 ± 0.5） d. In the control group, 40.6% of the patients were basically cured, 31.2% obviously improved and 71.8% improved （total rate of effectiveness）. The average treatment time for the improved cases was （12.8 ± 0.7） d. There were sig- nificant differences between the two groups in the total rate of effectiveness and the average treatment time for the improved cases （P 〈0. 05）. Conclusion： Spermatic cord seal-up injection for acute epididymitis deserves wide clinical application for its simple opera- tion, good tolerance, short therapeutic course and high safety and efficacy.
出处
《中华男科学杂志》
CAS
CSCD
2013年第7期622-625,共4页
National Journal of Andrology
关键词
精索封闭
急性附睾炎
药物封闭
spermatic cord seal-up injection
acute epididymitis
drug seal-up injection
