期刊文献+

血清脂联素与不稳定心绞痛及其危险因素的相关性 被引量:8

下载PDF
导出
摘要 目的分析血清脂联素(APN)在不稳定心绞痛诊疗中价值及APN与不稳定心绞痛(UA)危险因素的相关性。方法回顾分析老年冠状动脉粥样硬化性心脏病患者临床资料;比较UA组与健康对照组年龄、性别、C反应蛋白(CRP)、心肌肌钙蛋白I(cTnI)、APN、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及空腹血糖(FPG)浓度;分析UA组APN与冠心病(CAC)危险因素的相关性。结果 UA组血TC水平与对照组相比,差异无统计学意义(P>0.05);UA组血TG、LCL-C水平、CRP、cTnI水平均高于对照组(P<0.05);UA组血APN水平低于对照组(P<0.001);UA组血清APN与LDL、TG、CRP及FPG呈负相关(P<0.05)。结论血清APN在UA患者血液中呈现低水平,且血清APN与LDL、TG、CRP及FPG呈负相关;APN降低与cTnI升高是UA发生的独立风险因素。血清APN具有和常规血液学指标共同提示CAC发生、发展的价值。
作者 张俊
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第13期3082-3083,共2页 Chinese Journal of Gerontology
  • 相关文献

参考文献10

二级参考文献52

  • 1周秀军,李颖莉,秦勤,关欣,赵炳让.颈动脉内中膜厚度及斑块与冠心病的相关性[J].中国分子心脏病学杂志,2006,6(3):157-160. 被引量:4
  • 2初洪钢,郭瑞强,王世敏,孙彬,姜霞,孙有刚.主动脉瓣钙化与冠心病之间关系的探讨[J].中华超声影像学杂志,2006,15(8):634-635. 被引量:5
  • 3无.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206. 被引量:2072
  • 4曹霞,谢秀梅.老年钙化性心瓣膜病的病因学研究[J].临床心血管病杂志,2007,23(3):161-163. 被引量:22
  • 5Choon SS, Kyung WM, Seung YL, et al. Cardiovascular risk as- sessment with vascular function, carotid atherosclerosis and the UKPDS risk engine in Korean patients with newly diagnosed type 2 diabetes. Diabetes Metab ],2011,35:619 627.
  • 6Vogiatzis I, Tsikrika E, Sachpekidis V, et al. Factors affecting smoking resumption after acute coronary syndromes. Hellenic J Cardiol, 2010,51 : 294 300.
  • 7Arima H, Kubo M, Yonemoto K, et al. High-sensitivity C- reactive protein and coronary heart disease in a general population of Japanese:the hisayama study[J]. Eur Heart J,2008,29(9) :1110-1117.
  • 8Kahlak-ziembicka A,Tracz W,Przewlocki T, et al. Asso- ciation of increased carotid intima-media thickness with the extent of coronary artery disease[J]. Heart, 2004,90 (11) : 1286-1290.
  • 9Willerson JF,Ridker PM. Inflammation as a cardiovascu- lar risk factor[J]. Circulation,2004,109(21) :1102-1110.
  • 10Ridker PM,Cushman M, Stampfer MJ, et al. Plasma con- centration of C-reactive protein and risk of developing pe- ripheral vascular disease[J]. Circulation, 1998,97 (5) :425- 428.

共引文献70

同被引文献62

  • 1郭菁,熊蔚蔚,陶宇宏.抗菌药物使用情况1846例临床分析[J].北华大学学报(自然科学版),2012,13(4):438-440. 被引量:3
  • 2张媛.不同剂量阿托伐他汀对不稳定心绞痛血脂及预后的影响[J].天津医药,2004,32(8):517-518. 被引量:1
  • 3樊笑霞,吴飞.未成年人的脑脊液总蛋白质浓度与年龄的相关性[J].中国实验诊断学,2006,10(7):756-757. 被引量:2
  • 4全国eGFR课题协作组.MDRD方程在我国慢性肾脏病患者中的改良和评估[J].中华肾脏病杂志,2006,22(10):589-595. 被引量:708
  • 5赵冬林.男女性年龄相关骨丢失和体重的关系[J].国外医学:老年医学分册,1995,16(1):46-47.
  • 6Kansagara Devan,Fu Rongwei,Freeman Michele,et al. Intensive insulin therapy in hospitalized patients: a systematic review.[J]. Annals of Inter- nal Medicine,2011,1544:268-282.
  • 7Wang JieYang,Xiaochen Chu, Fuyong Chen,et al. The effects of xuefu zhuyu and shengmai on the evolution of syndromes and inflammatory markers in patients with unstable angina pectoris after percutaneous coro- nary intervention: a randomised controlled clinical trial. [J]. Evidence- based complementary and alternative medicine:eCAM,2013,2013:8964- 8967.
  • 8Ying Cui,Lihui Zheng,Ming Jiang,et al. Circulating microparticles in pa- tients with coronary heart disease and its correlation with interleukin-6 and C-reactive protein[J].Molecular Biology Reports,2013,4011:6437-6442.
  • 9Reyes Marcela, Gahagan Sheila,Dtaz Erik,et al. Relationship of Adiposity and Insulin Resistance Mediated by Inflammation in a Group of Over- weight and Obese Chilean Adoleseents[J].Nutrition Journal,2011,101:1-3.
  • 10Ogata Atsushi,Morishima Atsuyoshi,Hirano Toru,et al. Improvement of HbAlc during treatment with humanised anti-interleukin 6 receptor an- tibody, tocilizumab[J].ARD Online,2010,706:1164-1165.

引证文献8

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部