摘要
目的了解济南地区变应性鼻炎的常见变应原。方法回顾性分析济南地区1 138例确诊为变应性鼻炎患者的皮肤点刺试验结果,并根据年龄分为2～18岁未成年人组,19～70岁成人组;根据不同性别分为男性组和女性组。比较各组在变应原的阳性分布率上的差异。结果 1 138例变应性鼻炎患者中,有阳性反应843例(74.08%)。其中变应原阳性率由高到低依次为螨虫组合过敏745例(88.37%),蟑螂过敏363例(43.06%),花粉301例(35.71%),淡水鱼组合207例(24.56%),狗毛过敏139例(16.49%),猫毛过敏74例(8.78%),葎草过敏39例(4.63%),艾蒿过敏18例(2.14%),蛋清15例(1.78%),羊肉12例(1.42%),牛奶4例(0.47%),豆类3例(0.36%)。不同年龄组患者间蟑螂、狗毛的阳性率差异有统计学意义(P<0.01);不同性别间各种变应原的阳性率差异无统计学意义(P>0.05)。结论济南地区过敏性鼻炎的变应原主要是螨虫,其次为蟑螂及花粉,羊肉、牛奶、豆类等的比例极低;随着年龄的变化,部分变应原的阳性率有所改变;变应原的分布与性别无关。
Objective To explore the allergens of allergic rhinitis （AR） patients living in Jinan area. Methods The medical records of skin prick tests （SPT） performed in 1138 AR patients were retrospectively analyzed. The samples were divided into two groups based on age or on gender： the 2-18-year old group and the 19-70-year old group, or the male group and the female group. Sensitizing allergens were assessed and the positive rates of aeroallergens were com pared between the groups. Results There were 843 patients （74.08%） with positive prick test result, The aeroaller gens was as follows ： mite in 745 cases （ 88.37 % ）, cockroach in 363 cases （ 43.06 % ）, farina in 301 cases （ 35.71% ） freshwater fish in 207 cases （24.56%）, dog hair in 139 cases （ 16.49% ）, cat hair in 74 cases （8.78 % ）, scandent ho in 39 cases（4.63% ）, Felon herb in 18 cases（2.14% ）, albumen in 15 cases（ 1.78% ）, mutton in 12 cases（ 1.42% ） milk in 4 cases（0.43% ） and beans in 3 cases（0.36% ）. There was significant difference of distribution of cockroach and dog hair between the age groups （P 〈 0.01 ）. There was no significant difference between male and female patients neither in distribution of aeroallergens nor in single allergen and multiple allergens （ P 〉 0.05）. Conclusion The most common allergen in patients with allergic rbinitis in Jinan seems to be mite, and the second is cockroach and farina. Mutton, milk and been are rate allergen of allergic rhinitis patients in Jinan. With the age growing, part allergens posi tive rate are changed. The distribution of aeroallergens has no correlation with gender.
出处
《山东大学耳鼻喉眼学报》
CAS
2013年第3期25-26,29,共3页
Journal of Otolaryngology and Ophthalmology of Shandong University
关键词
变应性鼻炎
变应原
点刺试验
济南
Allergic rhinitis
Allergens
Skin prick test
Jinan
