摘要
目的研究乳腺癌患者血清中CEA、CA125、CA153的水平及其与生活质量的相关性。方法选择乳腺癌患者作为观察组、乳腺良性疾病患者作为良性对照组、健康体检者作为健康对照组,检测外周血中CEA、CA125、CA153的含量并观察生活质量相关指标。结果观察组患者CEA、CA125、CA153水平以及躯体功能、心理功能、社会功能、认知功能、总体生活质量评分明显高于良性对照组和健康对照组;躯体功能、心理功能、社会功能、认知功能、总体生活质量评分与CEA、CA125、CA153水平呈负相关。结论 CEA、CA125、CA153检查对乳腺癌的诊断具有积极的临床价值,且与生活质量密切相关。
Objective To study the level of CEA,CA125,CA153 in breast cancer patients and its correlation with quality of life. Methods the breast cancer patients were selected as observation group,benign breast disease patients as benign control group, and healthy people as healthy control group,the peripheral blood levels of CEA,CA125, CA153 were detected and quality of life were observed. Results The CEA,CA125,CA153 levels and physical function,psychological function,social function,cognitive function,overall quality of life scores of observation group were significantly higher than benign control group and healthy control group; physical function,psychological function,social function,cognitive function,overall quality of life score were negatively correlated with CEA,CA125,CA153 levels. Conclusion The clinical value of positive CEA,CA125,CA153 examination in the diagnosis of breast cancer,which is closely related with the quality of life.
出处
《中国医药科学》
2013年第13期123-124,135,共3页
China Medicine And Pharmacy
关键词
乳腺癌
癌胚抗原
肿瘤标志物
生活质量
Breast cancer
Tumor markers
Carcinoembryonic antigen
Quality of life