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非肥胖多囊卵巢综合征患者血清chemerin的变化及其与糖脂代谢相关性的研究 被引量：3

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摘要 目的研究非肥胖多囊卵巢综合征(PCOS)患者血清chemerin水平的变化及其与糖脂代谢的关系。方法根据2003年鹿特丹会议制定的诊断标准选择PCOS患者23例,同时选择正常月经周期的健康女性20例作为正常对照组。采用酶联免疫吸附法(ELISA)检测血清中chemerin的水平,同时抽取血样测定血糖、胰岛素、总胆固醇(TC)、甘油酸三脂(TG)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)水平。结果 PCOS患者血清chemerin的水平明显高于正常对照组,且PCOS患者血清chemerin的水平与空腹血糖、2h后血糖、空腹胰岛素、2h后胰岛素、TC、TG、LDL和胰岛素抵抗指数(HOMA-IRI)成正相关,与HDL水平呈负相关。结论 PCOS患者血清chemerin水平的变化与其糖脂代谢异常有关。
作者 李志英 王克超
机构地区 湖南省嘉禾县中医院妇产科 中南大学现代分析测试中心
出处 《中国医药指南》 2013年第19期158-159,共2页 Guide of China Medicine
关键词 多囊卵巢综合征 chemerin炎症 糖脂代谢 研究
分类号 R711.75 [医药卫生—妇产科学]
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二级参考文献16

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共引文献53

同被引文献46

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中国医药指南
2013年 第19期

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