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原发性乳腺淋巴瘤的临床、病理及影像学特点 被引量:4

Clinical, pathological, and imaging features of primary breast lymphoma
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摘要 原发性乳腺淋巴瘤极少见,其治疗方法与乳腺癌不同,预后比乳腺癌差。该疾病的临床特点及影像学表现与乳腺癌有很大重叠,主要依靠病理诊断和分型。弥漫性大B细胞淋巴瘤是最常见的病理类型。细针针吸细胞学检查的准确率高于冷冻检查,但两者均难以完全正确诊断。临床上患者通常表现为无痛性肿块,为单个或多结节,少数患者呈弥漫浸润使乳房变硬,局部皮肤受累。原发性乳腺淋巴瘤X线表现大致可分为结节或肿块型及致密浸润型,钙化、毛刺、乳头内陷等罕见。其超声表现复杂多样,可表现为低回声或高回声,部分呈类囊肿样极低回声,伴后方回声增强或无改变,内部血流较丰富。关于乳腺淋巴瘤MRI表现的文献主要见于个案报道,表现为T1WI低信号,T2WI稍高信号,增强扫描早期明显强化,曲线以流出型多见。MRI检查在乳腺淋巴瘤诊断中的作用还不确定。 Primary breast lymphoma is a rare disease, whose treatment and prognosis are different from breast carcinoma. Based upon clinical and imaging manifestations, it is difficult to differentiate breast lymphoma from breast carcinoma. Biopsy is essential for definite diagnosis. Diffuse large B-cell lymphoma is the most common histological type. The accuracy of fine needle aspiration cytology is higher than that of frozen section, but neither can be completely correct. Mammographic features of breast lynlphoma include a solitary mass or diffuse increased opacity. Spiculation, calcification or nipple retraction is rare. Ultrasonographic appearance of breast lymphoma is not specific. Hypervascular mass with an echogenic boundary, hypoechoic or almost anechoic, mixed hypo- and hyperechoic in echo pattern, and with no posterior acoustic phenomena is the main ultrasonographic features. MRI appearance of breast lymphoma is described mainly in case reports. Masses with hypoin- tense on T1WI and hyperintense on T2WI show rapid and strong enhancement in early phase and washout in delayed phase on dynamic sequence. The value of MRI in diagnosis of breast lymphoma is uncertain.
出处 《肿瘤影像学》 2013年第2期81-83,共3页 Oncoradiology
关键词 原发性乳腺淋巴瘤 X线 超声 磁共振 Primary breast lymphoma X-ray Ultrasound Magnetic resonance imaging
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共引文献81

同被引文献31

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