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脑胶质肉瘤1例报告并文献复习 被引量:1

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摘要 目的探讨脑胶质肉瘤的临床特征、影像学特征及治疗方法。方法回顾性分析1例脑胶质肉瘤患者临床资料,并结合文献进行复习。结果本例患者手术切除肿瘤,术后6月复发,术后7月死亡;脑胶质肉瘤CT平扫主要为混杂密度影,瘤灶内可见囊变、出血、坏死及钙化,边界不清,瘤周水肿明显,增强后呈高密度边界清晰影,不均匀环状强化;MRI平扫在T1WI和T2WI均为混杂信号,边界不清,占位效应明显,增强后呈现明显厚壁环形强化;HE染色:光镜下可见肿瘤主要由胶质母细胞瘤和肉瘤两种混合成分组成;免疫组化示神经胶质纤维酸性蛋白(+)、S-100蛋白(+)、波形蛋白(+)。结论诊断脑胶质肉瘤需结合影像表现、病理组织学及免疫组化结果,尽可能全切除肿瘤是目前唯一有效的治疗方法,术后辅助放、化疗可减少复发及转移。
出处 《中国临床神经外科杂志》 2013年第7期433-435,共3页 Chinese Journal of Clinical Neurosurgery
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