摘要
目的观察综合治理后燃煤污染型地方性氟中毒(简称地氟病)病区人群心电图改变情况。方法2011年,选择贵州省毕节市燃煤污染型地氟病病区人群,按病情轻重和综合治理时间长短分为4个组:轻病区+治理短组(沙地村52人)、轻病区+治理长组(下坝村58人)、重病区+治理短组(毛栗平村52人)、重病区+治理长组(中屯村60人),以贵阳市人群为非病区对照组(沙文新寨57人),采用同步导联心电图机测定观察人群心电图。结果与非病区对照组[47.4%(27/57)]比较,重病区+治理短组[71.2%(37/52)]、重病区+治理长组[66.7%(40/60)]心电图异常率明显升高(x2值分别为6.346、4.448,P均〈0.05),而轻病区+治理短组[61.5%(32/52)]和轻病区+治理长组[56.9%(33/58)]未见明显改变(x2值分别为2.199、1.046,P均〉0.05);相同病区不同治理时间的人群心电图异常率比较,差异无统计学意义(轻、重病区)(2值分别为0.244、0.261,P均〉0.05)。结论地氟病重病区人群心电图异常发生率较高,通过一定时间综合治理后地氟病病区人群心电图异常率降低不明显。
Objective To examine the eleetreeardiogram(ECG) changes in the populations lived in coal- burning-borne endemic fluorosis areas after comprehensive treatment and to select indexes for evaluating health improvement. Methods People lived in coal-burning-borne endemic fluomsis areas in Bijie City were selected and divided into four groups according the length of time of comprehensive treatment and the severity of fluorosis in 2011: light ill area with shorter treatment time (Chadi Village 52 people), light ill area with longer treatment time (Xiaba Village 58 people), seriously ill area with shorter treatment time (Maoliping Village 52 people) and seriously ill area with longer treatment time(Zhongtun Village 60 people). In addition, 57 people in Shawenxin Village Guiyang City were selected as non-fluorosis controls. Synchronous-lead ECG machine was used to observe ECG of the populations. Results As compared to the non-fluorosis control group [47.4% (27/57)], there were significant differences in the abnormal rate of ECG in seriously ill area with shorter treatment time and seriously ill area with longer treatment time groups[71.2%(37/52), 66.7%(40/60), X2 = 6.346, 4.448, all P 〈 0.05] ; but no significant changes of the abnormal rate of ECG were found in light ill area with shorter treatment time and light ill area with longer treatment time groups[61.5%(32/52), 56.9%(33/58), X2 = 2.199, 1.046, all P 〉 0.05]. Among the same diseased areas with different length of treatment time, no significant difference of the abnormal rate of ECG wasobserved(X2 = 0.244, 0.261 in light and seriously ill areas, respectively, all P 〉 0.05). Conclusions Significantly increased abnormal rate of ECG is observed in seriously ill areas. However, after a certain period of time of comprehensive prevention treatment, ECG abnormal rate is not changed significantly.
出处
《中华地方病学杂志》
CAS
CSCD
北大核心
2013年第4期424-426,共3页
Chinese Journal of Endemiology
基金
国家自然科学基金(81160335)
国际科技合作项目(2010DFB30530)
科技部支撑计划课题(2011BAZ03220)
贵州省科技厅项目(黔科合外G字[2011]7014号)
贵阳医学院创新基金(S201104)
关键词
氟
心电描记术
数据收集
Fluorine
Electrocardiography
Data collection