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小儿急性病毒性脑炎超早期诊断依据的Logistic回归分析 被引量:5

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摘要 目的回顾性分析小儿急性病毒性脑炎(VE)的临床资料,分析各超早期诊断依据因素的特异性、敏感性价值,建立回归模型。方法选取2012-01—2013-01在我院住院患儿(具有诊断依据中任变量2项),共266例,其中确诊VE患儿189例,非VE患儿77例。应以"中枢神经系统感染待排"初诊的患儿为研究对象,用Logistic回归分析VE超早期诊断因素的灵敏度和特异度,将有统计学意义的因素构建Logistic回归模型。结果在病毒性脑炎的超早期诊断依据变量中,频繁呕吐、意识障碍、共济失调、病理征阳性、腰椎穿刺压力增高、脑脊液检验异常、甘露醇诊断性治疗有效的影响差异有统计学意义(P<0.05)。以此得出的Logistic回归概率模型灵敏度为95.2%,特异度为88.3%,Logistic回归分析的显著性检验统计量卡方值提示Logistic回归方程有统计学意义(P<0.001)。结论应用Logistic回归分析可以建立合适的VE超早期诊断模型,有较高的灵敏度和特异度。
出处 《中国实用神经疾病杂志》 2013年第14期30-32,共3页 Chinese Journal of Practical Nervous Diseases
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