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244株鲍曼不动杆菌临床分布特点及药敏结果分析 被引量:1

Clinical distribution characteristics and drug sensitivity analysis of 244 strains Acinetobacter baumannii
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摘要 目的:通过对微生物室分离的鲍曼不动杆菌检测结果进行分析,了解本院鲍曼不动杆菌的临床分布和耐药情况,以加强I临床医师对鲍曼不动杆菌感染的预防和控制。方法:收集2012年1月-2012年12月检验科微生物室分离的244株鲍曼不动杆菌,进行药敏检测,分析其临床分布特点和药敏情况。结果:244株鲍曼不动杆菌主要来源于ICU病房(32.18%),脑外科(19.54%),烧伤科(12.64%),呼吸内科(10.35%);标本以痰液为主(78.16%),其次为脓液(17.24%);药敏结果显示本院分离的鲍曼不动杆菌对氨苄西林、头孢唑啉、头孢西丁等耐药率为100%,其次为头孢呋新钠和头孢呋新酯(96.30%),头孢匹美(86.59%),左氧氟沙星(78.16%),头孢噻肟(77.91%),丁胺卡那霉素(77.11%),头孢他啶(77.01%),哌拉西林/他唑巴坦(70.73%),美罗培南(63.41%),亚胺培南(62.07%),头孢哌酮/舒巴坦(32.14%),耐药率最低的药物为米诺环素(28.00%)。大部分为多重耐药菌株(70.12%)。结论:本院鲍曼不动杆菌耐药现象非常严重,各临床科室应注重抗生素的合理使用,加强预防和控制鲍曼不动杆菌感染。 Objective : To enhance the prevention and control of Acinebacter baumannii infection of clinicians through anMyzing the distribution and resistance characteristic of clinical Acinetobacter baumannii. Methods : 244 strains of Acinetobacter baumannii were collected from January to December in 2012,drug susceptibility test was carried. The distribution of clinical characteristics and drug sensitivity were analyzed.Result8 : 244 Acinetobacter baumannii mainly isolated from the ICU (32.18%), neurosurgery (19.54%), bums (12.64%), respiratory medicine (10.35%); sputum was the main source of specimens(78.16%), followed by of pus (17.24%); susceptibility results show the resistance rates to ampicillin, cefazolin, cefoxitin resistance rate of 100%, followed by cefuroxime sodium and cefuroxime ester (96.30%), cefpiramide America (86.59%), levofloxacin (78.16%), cefotaxime (77.91%), amikacin (77.11%), ceftazidime (77.01%), piperacillin / tazobactam (70.73%), meropenem (63.41%), imipenem (62.07%), cefoperazone / sulbactam (32.14%), the lowest rate of drug resistance to minocycline (28.00%). Most of the Acinetobacter baumannis are multi- resistant strains (70.12%).Conclusions : Resistant condition of Acinetobacter baumannii in this hospital is very serious, clinical departments should focus on the rational use of antibiotics, strengthen the prevention and control of Acinetobacter baumanniiinfections.
出处 《医学检验与临床》 2013年第3期39-40,32,共3页 Medical Laboratory Science and Clinics
关键词 鲍曼不动杆菌 多重耐药性抗生素 Acinetobacter baumannii Multidrug resistance Antibiotics
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