期刊文献+

迈之灵片治疗静脉血管疾病临床应用的Meta分析 被引量:3

Meta-analysis of clinical application on vein disease of Aescuven Forte Tablets
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摘要 目的评价迈之灵片治疗静脉血管疾病的疗效与安全性。方法计算机检索中国知网(CNKI)的中国期刊全文数据库、中国生物医学文献数据库、维普资讯网中文科技期刊数据库及万方数据库,选取并评价迈之灵片治疗静脉血管疾病的对照试验文献,然后采用RevMan 5.0软件进行分析。结果共纳入14篇临床研究文献,共计病例数2 772例。在总有效率方面,14个临床对照试验的Meta分析结果显示,两组间差异有统计学意义(P<0.01)。结论现有的试验结果表明,迈之灵片与其他药物比较,可以提高静脉血管疾病的治疗总有效率。受纳入研究的治疗和数量限制,迈之灵片治疗静脉血管疾病的疗效与安全性需要更多高质量的、大样本的、双盲的随机对照试验加以证实。 Objective To evaluate the effect and safety of Aescuven Forte Tablets for treating venous disease. Methods Establishing database by retrieval via the Database of Chinese Journal of CNKI, Medical Database of China Biomedicine, VIP Database of China Science and Technology and Wanfang date pase, then screened control clinical studies on Aescuven Forte tablets for treating venous disease, and analyzed all data by using RevMan 5.0 software. Results Totally 14 theses were included in the meta - analysis,including 2 772 patient eases. As the meta - analysis results of the 14 clinical control trials shown, the group difference was meaningful statistically ( P 〈 0.01 ) for the total effective rate. Conclusion The results of our experiment indicated that, compared with other medicines, Aescuven Forte Tablets was possible in enhancing the total effective rate of venous disease treatments. Limited by the sample quantity of clinical studies, more high quality, large sample, double - blind control trials concerning the effectiveness and safety of Aescuven Forte Tablets in venous disease treat- ment were in call for further proving.
出处 《药学研究》 CAS 2013年第7期412-415,共4页 Journal of Pharmaceutical Research
关键词 迈之灵片 静脉血管疾病 临床应用 META分析 Aescuven forte Venous disease Clinical application Meta - analysis
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