摘要
目的:比较不同质子泵抑制剂治疗消化性溃疡出血的疗效,以供临床工作参考。方法:选择2009年10月-2012年9月笔者所在医院收治的105例消化性溃疡出血患者作为研究对象,根据随机法分为A组和B组,均接受包括抗感染、止血、胃黏膜保护、抑酸等对症治疗。A组应用注射用奥美拉唑钠,B组应用注射用泮托拉唑钠。治疗7d后,对比两组患者的有效性和安全性。结果:B组总有效率明显高于A组,差异有统计学意义(P<0.05)。治疗期间,两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:质子泵抑制剂在消化性溃疡出血的治疗中具有重要的价值,其中泮托拉唑疗效具有一定的优越性,临床应用前景较好。
Objective： To compare the different proton pump inhibitors in the treatment of peptic ulcer bleeding, clinical work for reference.Methods： From October 2009 to September 2012, 105 cases as research subjects, grouped according to the random method was accepted, including anti-infection, bleeding, symptomatic treatment of gastric mucosal protective, acid-suppressing patients with peptic ulcer bleeding. Group A was given omeprazole, group B was given pantoprazole.Contrasted the difference of efficacy and safety.Results： The effectiveness of group B was significantly higher than group A, the difference was statistically signifieant（P〈0.05）.The incidence of adverse reactions was not statistically significant between two groups（P〉O.O5）.Conclusion： Proton pump inhibitors in the treatment of peptic ulcer bleeding has an important value, the efficacy of pantoprozole has certain advantages, better prospects for clinical application.
出处
《中外医学研究》
2013年第22期9-10,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
