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急性冠脉综合征应用替罗非班的临床观察

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摘要 目的:探讨替罗非班在急性冠脉综合征(ACS)治疗中的应用价值。方法:116例ACS患者随机等分为2组,2组均进行常规治疗,观察组加用替罗非班,对比2组疗效。结果:观察组不良心脏事件发生率(5.2%)明显低于对照组(29.3%),差异有显著统计学意义(P<0.01)。观察组出血并发症发生率(6.9%)高于对照组(5.2%),差异无统计学意义(P>0.05)。结论替罗非班治疗ACS,疗效满意,预后良好。
作者 杨青
机构地区 南阳市第二人民医院心血管内科
出处 《中国伤残医学》 2013年第7期223-224,共2页 Chinese Journal of Trauma and Disability Medicine
关键词 急性冠脉综合征 替罗非班 心肌梗死
分类号 R541.4 [医药卫生—心血管疾病]
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  • 1[1]Davies MJ. The composition of coronary-artery plaques[J]. N Engl J Med,1997;336:1312-1314.
  • 2[2]Granger CB, Hirsch J,Califf RM, et o1. Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infartion: results from the GUSTO-1 trial[J]. Circulation,1996:93:870-878.
  • 3[3]CAPRIE Steering Committee. A randomised,blinded,trial of clopidogrel versus aspirin in patients at risk of ischaemic events ( CAPRIE ) [ J ]. Lancet, 1996:348:1329-1339.
  • 4[4]Coller BS,Peerschke EI,Scudder LE et al. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthen-ic-like state in normal platelets and binds to glycoprotein Ⅱ b/Ⅲ a [ J ]. J Clin Invest, 1983:72:325-338.
  • 5[5]The EPIC Investigators: Use of a monoclonal antibody directed against the platelet glycoprotein Ⅱ b/Ⅲ a in high-risk coronary an, gioplasty [ J ]. N Engl J Med,1994:330:956-961.
  • 6[6]EPISTENT Investigators. Randomized placebo-controlled and balloon-angioplasty controlled trial to assess safety of coronary stenting with use of platelet glycoprotein Ⅱb/Ⅲa blockade[J]. Lancet,1998 :352 :87-92.
  • 7[7]EPILOG Investigators. platelet glycoprotein Ⅱ b/Ⅲ a blockade with abciximab with low-dose heparin during percutaneous coronary revascularization [ J ]. N Engl J Med,1997:336:1689-1696.
  • 8[8]CAPTURE Investigators. Randomized placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE study [ J ]. Lancet, 1997:349:1429-1435.
  • 9[9]Brener SJ,Barr LA,Burchenal JEB,et al. A randomized,placebo-cotrolled trial of platelet glycoprotein Ⅱ b/M a blockade with primary angioplasty for acute myocardial infarction [ J ]. Circulation, 1998:98:734-741.
  • 10[10]IMPACT II Investigators. Rrandomized placebo-cotrolled trial of effect of eptifibatide on complications of percutaneous coronary intervention:IMPACT Ⅱ[ J ].Lancet, 1997:349:1422-1428.

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中国伤残医学
2013年 第7期

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