摘要
目的探讨降钙素原（PCT）及C反应蛋白（CRP）在新生儿病理性黄疸病因分析中的应用价值。方法对2011年6月～2013年3月在我院新生儿科住院的诊断为新生儿病理性黄疸83例临床资料进行回顾性分析。根据病因及实验室检查结果分为感染组及非感染组，分析两组血清中PCT、CRP水平变化。结果新生儿黄疸感染组PCT及CRP均明显高于非感染组，差异有统计学意义（P〈0．05）。PCT敏感性为92．0％，特异性87．9％，CRP敏感性为68．0％，特异性63．8％，对细菌感染的诊断PCT比CRP具有更高的敏感性及特异性。结论血清PCT检测优于血清CRP检测，可用于新生儿病理性黄疸细菌感染的诊断依据，对指导临床合理应用抗生素有重要意义。
Objective To investigate the application value of procalcitonin and C-reactive protein in the etiological analysis of newborn pathological jaundice. Methods 83 cases＇s clinical datum of newborn pathological jaundice in the neonatology department from June 2011 to March 2013 were selected and retrospectively analyzed. They were divided into infection group and non-infection group according to the etiology and laboratory test results, analyzed the changes of serum PCT, CRP levels in the two groups. Results the PCT, CRP levels in the newborn jaundice infection group were significantly higher than those in the non-infected group, P 〈 0.05, there had statistically significant difference. PCT sensitivity was 92.0%, specificity was 87.9%; CRP sensitivity was 68.0%, specificity was 63.8%, PCT had higher sensitivity and specificity than CRD in the diagnosis of bacterial infection. Conclusion Serum PCT test is superior to serum CRP test, it can be used for bacterial infections diagnosis in newborn pathological jaundice. It has important significance for clinical rational use of antibiotics.
出处
《中国医药科学》
2013年第15期209-210,214,共3页
China Medicine And Pharmacy
关键词
降钙素原
C反应蛋白
新生儿黄疸
Procalcitonin
C-reactive protein
Newborn jaundice
