摘要
目的探讨全直肠系膜切除术（TME）与传统直肠癌根治术治疗直肠癌的临床疗效。方法选择2009年10月-2010年10月我院就诊的120例直肠癌患者临床资料进行回顾性分析，根据治疗方法不同分为观察组与对照组，每组各60例，观察组采用TME治疗，对照组采用传统直肠癌根治术进行治疗。观察两组患者的平均手术时间、平均术中出血量、肛门排气时间、术后住院时间、局部复发及转移率、5年生存率情况及术后并发症情况。结果治疗后，观察组患者平均手术时间、平均术中出血量、肛门排气时间、术后住院时间、5年生存率、局部复发率明显优于对照组，差异具有统计学意义（P〈0．05）。术后观察组并发症发生率（6．7％）明显低于对照组（16．7％），差异具有统计学意义（P〈0．05）。结论规范的TME手术可提高患者5年生存率、提高保肛率、以及保留盆腔自主神经，降低术后复发率，尽可能地保留患者的正常生理功能，具有推广价值。
Objective To compare the clinical effect of Total mesorectal excision （TME）and traditional radical operation on treatment of rectal cancer. Methods The clinical data of 120 rectal cancer patients who were in hospital from October 2009 to October 2010 were retrospectively analyzed and divided into the control group and experiment group according to the treatment method, each group of 60 cases.The experiment group was given TME,and the control group was treated by traditional radical operation. The average operation time,the average amount of bleeding,anal exhaust time,length of stay,the 5-year survival rate and postoperative complications of the two groups were compared. Results Th~ average operation time, the average amount of bleeding,anal exhaust time,length of stay and the 5-year survival rate of experiment group were better than those of the control group,the difference was statistically significant （P 〈 0.05）.The complication rate of the experiment group （6.7%） was lower than that of control group （16.7%）, the difference was statistically significant（P 〈 0.05）. Conclusion Standard TME operation can improve the 5 year survival rates of patients,improve the rate of anal preservation,and pelvic autonomic nerve preservation,reduce the recurrence,as far as the normal physiological function reserve of patients.TME has the value of popularization.
出处
《中国医药科学》
2013年第15期211-212,共2页
China Medicine And Pharmacy
关键词
直肠癌
全直肠系膜切除术
转移率
Rectal cancer
Total mesorectal excision
Metastasis rate
