女性月经周期对丙泊酚诱导意识消失血浆靶浓度半数有效剂量的影响被引量：3

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摘要女性进入生育期后，雌激素和孕激素在月经周期中呈波动性变化，由于孕激素及其代谢物具有镇静、抗焦虑、抗惊厥和麻醉效应，与卵泡期相比，黄体期患者不仅可以减少吸入麻醉药七氟烷的用量，麻醉诱导所需的丙泊酚用量也明显减少。本研究通过序贯试验法测定并计算不同月经周期的女性患者丙泊酚诱导意识消失的血浆靶浓度半数有效剂量（EC50），以进一步证实该结果。

作者唐郁文谭华楼艾飞

机构地区浙江大学医学院附属妇产科医院麻醉科

出处《上海医学》 CAS CSCD 北大核心 2013年第6期558-559,共2页 Shanghai Medical Journal

基金浙江省教育厅资助课题(Y200909281)

关键词女性月经周期半数有效剂量意识消失丙泊酚靶浓度血浆女性患者吸入麻醉药

分类号 R614 [医药卫生—麻醉学]

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参考文献12

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