摘要
目的探讨VMA检测方法及结果在临床中的应用。方法回顾分析了本院1300例普通高血压患者、嗜铬细胞瘤51例、神经母细胞瘤2例、交感神经节瘤1例、肾上腺肿瘤22例、正常健康对照组50例,24h尿中VMA的含量。结果 VMA的含量在成人间性别、年龄无统计学意义(P>0.05),各疾病组与正常对照组比较有统计学意义(P<0.05)。嗜铬细胞瘤患者与其他疾病组对比有统计学意义(P<0.01)各组疾病治疗后与治疗前相比VMA的含量有统计学意义(P<0.01),表明治疗有效;同位素放疗法或化疗与手术法相比较无统计学意义(P>0.05)表明治疗方法无差异。结论 24小时尿VMA是诊断、治疗、预后观察儿萘酚胺代谢疾病最有效指标之一。
Objective To explore the clinical application of the detection method and result of VMA in urine. Meth- ods DReview the content of 24 hours urine VMA in all the cases of this hospital about ordinary hypertension patients （ 1300）, Pheochromocytoma in 51 cases, neur~.blastoma in 2 cases, paraganglioma sympathic in 1 cases, adrenal tumor in 22 cases, normal healthy controls groups in 50 cases. Results The content of VMA in adults no significant difference of gender and age （P〈0.05）. Each disease group compared with the normal group are significantly different （P〈0.05）. Pheochromocytoma patients and other disease groups s difference is very significant （P〈0.01）. The disease after treat- ment with treatment than before, the content of VMA have significant difference , shows that the effective treatment; I- sotopes chemotherapy and radiation therapy or surgery, compared to a no significant differences （P〉0.05） , shows.tllat the treatment is no difference. Conclusion 24 hour urine VMA is diagnosis, treatment, prognosis, naphthol amine me- tabolism disease the most effective indicator.
出处
《中国实验诊断学》
2013年第7期1264-1267,共4页
Chinese Journal of Laboratory Diagnosis
基金
深圳市科技计划项目(201102154)
