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An efficient synthesis of substituted 1,4-diazepines by a Pd catalyzed amination and sequential hydrogenation condensation 被引量:2

An efficient synthesis of substituted 1,4-diazepines by a Pd catalyzed amination and sequential hydrogenation condensation
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摘要 An efficient synthesis of substituted 1,4-diazepines is developed.The accessible intermediates have been obtained via Pd-catalyzed amination.The subsequent hydrogenation and intramolecular condensation sequences could be conducted successively in one pot without special operation.The mild and general strategy enables the synthesis of various substituted 1,4-diazepines in high yields. An efficient synthesis of substituted 1,4-diazepines is developed.The accessible intermediates have been obtained via Pd-catalyzed amination.The subsequent hydrogenation and intramolecular condensation sequences could be conducted successively in one pot without special operation.The mild and general strategy enables the synthesis of various substituted 1,4-diazepines in high yields.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第8期743-746,共4页 中国化学快报(英文版)
基金 supported by National Natural Science Foundation of China(No.81102322)
关键词 1 4-Diazepines Pd-catalyzed amination Hydrogenation Intramolecular condensation 1,4-Diazepines Pd-catalyzed amination Hydrogenation Intramolecular condensation
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