摘要
目的:评价马来酸桂哌齐特注射液治疗急性脑梗死的疗效及不良反应。方法:将2010年5月~2011年7月收治的100例急性脑梗死患者随机分为两组,观察组50例给予马来酸桂哌齐特注射液治疗,对照组50例给予疏血通注射液治疗,比较两组治疗前、后病残程度评级、神经功能缺损情况及临床疗效。结果:观察组总有效率为90%,对照组总有效率为70%,两组差异有统计学意义(P<0.05),两组治疗后病残程度评级、神经功能缺损情况比较,差异有统计学意义(P<0.05);两组均未出现明显的不良反应。结论:马来酸桂哌齐特是治疗脑梗死的一种疗效肯定、且安全的药物,值得临床推广应用。
Objective:To evaluate effect of cinepazide maleate on acute cerebral infarction and its side effect.Methods:A total of 100patients with acute cerebral infarction admitted from May 2010-July 2011were randomly divided into two groups by half,patients in observation group had cinepazide maleate injection,and patients in control group had Shuxuetong injection.Disease rating and neurological impairment scale were performed before and after treatment,and the efficacy was also compared between two groups.Results:Total efficacy was 90% in observation group,70% in control group,with significant difference between two groups(P0.05).There were significant differences in disease rating and neurological impairment scale between two groups(P0.05).And no significant side effect occurred in both two groups.Conclusions:Cinepazide maleate is effective on treating acute cerebral infarction.It is safe,and is worthy clinical application.
出处
《海南医学院学报》
CAS
2013年第9期1253-1255,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210790)~~
关键词
脑梗死
马来酸桂哌齐特
疏血通
神经功能
Acute cerebral infarction
Cinepazide maleate
Shuxuetong
Neurological function