摘要
采用 2× 2析因分析和石墨炉原子吸收仪测定 ,发现缺碘 (ID)育龄女性吸烟者 (SI)全血硒和铅镉有毒元素含量有明显的交互影响 (P均 <0 0 1) ,血液Se含量 2 6 5± 8 0 9μg/L ,明显低于对照 (34 2± 7 6 4μg/L :Pb143 7± 2 34μg/L和Cd10 5± 4 83μg/L明显高于对照 (97 6± 2 1 7μg/L和 3 8±2 34μg/L。SI单因素亦见有使Se含量减低和Pb、Cd含量增高的现象 :ID单因素仅见有Pb含量增高 (P <0 0 1)。提示 :SI和ID共存时对人体内微量元素的吸收和贮存有抑制作用 ,同时二者共存时可促进有毒元素Pb和Cd的吸收。该ID流行区人群的Pb含量增高 ,与地处交通线 ,受汽车尾气排放铅尘污染 ,造成Pb高本底的可能亦不能排除。
The study which adopted 2×2 factor-factorial design principle and graphite oven atomic absorptiometer shows that the changes of contents of the toxic elements such like Selenium(Se),Lead(Pb) and Cadmiun(Cd) in women with iodine deficiency(ID)and smoke inhalation(SI) have distinct mutual effect(P av <0 01).The blood Se's content was 26 5±8 09μg/L,which obviously lower than that of the control(34 2±7 64μg/L);Pb was 143 7±2 34μg/L and Cd was 10 5±4 83μg/L,which obviously higher than the control(97 6±21 7μg/L and 3 8±2 34μg/L).The increase of Se and the decrease of Pb and Cd can be seen with SI single factor,but with ID factor only the increase of Pb can be seen (P<0 01).The results showed that the joint action effects of ID and SI inhibit the absorb and store of trace element inside the human body,in the same time,the coexist of ID and SI can promote the absorb of the toxic elements:Pb and Cd.The population in the ID epidemic area with high Pb content of cause can not rule out the possibility that it is located in communication lines,the effect of automobile's tail gas which promote the lead dust's pollution and make the high Pb background.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2000年第11期975-976,共2页
Chinese Journal of Public Health
基金
湖北省科委课题!(1 998B2 3)
关键词
吸烟
缺碘
硒
铅
镉
联合作用
全血
育龄
妇女
Smoke inhalation(SI)\ Iodine deficiency(ID)\ Joint action\ Selenium(Se)\ Lead(Pb)\ Cadmium(Cd)\ Blood\ Childbearing women
