摘要
目的:评价CT引导下毁损腹腔神经丛结合中药治疗胰腺癌癌痛的临床疗效,并对影响止痛效果的因素进行初步探讨。方法:30例胰腺癌患者均经临床三阶梯止痛效果不佳而行腹腔神经丛毁损术。行双侧穿刺者,每侧注入毁损剂无水乙醇10mL;单侧者注入无水乙醇15 mL。30例患者按随机数字表分为A组、B组、C组,A组10例采用三阶梯止痛法治疗,B组10例采用腹腔神经丛毁损术治疗,C组10例采用腹腔神经丛毁损及中药治疗。所有患者术前与术后1周均采用VAS评分。结果:术前与术后1周三组VAS评分比较,C组与A组、B组比较差异有统计学意义(P<0.05)。结论:CT引导下腹腔神经丛毁损结合中药治疗胰腺癌癌痛患者,是一种安全而有效,不良反应小的治疗方法,且有较好的止痛效果。
Objective：To evaluate neurolytic celiac plexus block guided by computerized tomography（CT） combined with Chinese medicine in treating pancreatic cancer pain,and to discuss the influential factors of the analgesic effect initially.Methods：30 patients with pancreatic cancer were all treated with neurolytic celiac plexus block without good effect of analgesic through the three steps.anhydrous ethanol 10 mL was injected each side when patients were carried out with Bilateral puncture,and anhydrous ethanol 15 mL was injected when Unilateral puncture.30 patients were divided into group A,group B and group C according to random number table.group A of 10 cases were given three step analgesic treatment,group B of 10 cases were given neurolytic celiac plexus block,and group C of 10 cases were treated with neurolytic celiac plexus block and Chinese medicine.VAS score was used preoperative and one week after operation.Results：Comparison of VAS score in the three groups preoperative and one week after operation showed that the difference of group C compared with group A and group B was statistically significant（P0.05）.Conclusion：Neurolytic celiac plexus block guided by computerized tomography combined with Chinese medicine in treating pancreatic cancer pain is a kind of treatment method of safety and efficiency,and small adverse reactions,and with good analgesic effect.
出处
《中医学报》
CAS
2013年第8期1102-1103,共2页
Acta Chinese Medicine
基金
国家自然科学基金项目(编号:30860286)
关键词
胰腺癌
疼痛
腹腔神经节毁损术
辨证论治
三阶梯止痛法
腹腔神经节
无水乙醇
pancreatic cancer
pain
neurolytic celiac plexus block
syndrome differentiation and treatment
three step analgesic treatment
celiac ganglia
anhydrous ethanol
