摘要
目的:探讨丹参注射液对高血压合并左心衰患者心功能的影响,为临床治疗提供参考。方法:选取我院收治的52例高血压并发急性左心衰竭的患者作为研究对象,随机分为治疗组30例和对照组22例;对照组采用心力衰竭的常规治疗方法,治疗组在对照组基础上加用丹参注射液;对比2组患者治疗前后LVEDD、LVESD、LVEF、LVMW、△T%的变化,并对比治疗后2组心功能改善率;同时分析2组血脂、血糖的变化水平。结果:经过治疗后,治疗组心功能改善总有效率为93.34%,对照组为77.27%,2组相比,具有统计学意义(χ2=10.039,P<0.05);治疗后2组患者LVEDD、LVESD缩小,LVMW减轻,LVEF、△T上升;其中治疗组LVEDD、LVMW、LVEF改善明显优于对照组(P<0.05);治疗组治疗后血糖、三酰甘油、低密度脂蛋白水平明显低于对照组,总胆固醇、高密度脂蛋白水平高于对照组,2组相比差异具有统计学意义(P<0.05)。结论:丹参注射液可以保护心肌细胞,改善心力衰竭患者的心功能,值得临床推广应用。
Objective： To explore effect of Danshen injections on patients with hypertension and left ventricular failure in order to provide clinical guidance.Methods： Fifty-two patients were randomly divided into two groups： 22 patients in control group received theconventional treatment,30 patients in observation group received Danshen injection in addition. We compared LVEDD,LVESD,LVEF,LVMW,△T% change between 2 groups,and compared t cardiac function improvement rate; analyzed serum lipids and glucose. Results： The observation group had total effective rate of 93. 34% ,compared to 77. 27% in the control group （ χ2= 10. 039,P ＆lt;0. 05） ; After treatment it was observed in both groups that LVEDD and LVESD reduced,LVMW relieved,LVEF and △T rose; and theobservation group improved more significantly than the control group （ P ＆lt; 0. 05） . Conclusion： Danshen injections can protect myocardial cells,and improve the cardiac function in patients with heart failure.
出处
《世界中医药》
CAS
2013年第6期623-625,共3页
World Chinese Medicine
关键词
丹参注射液
高血压
心力衰竭
心功能
Danshen injections
Hypertension
Heart Failure
Cardiac function
