摘要
目的了解和分析本院药品不良反应(ADR)的发生情况,为临床合理用药提供参考。方法调查分析本院2005～2011年期间收集的共2 112份ADR报告,从ADR上报人员、类型、患者一般情况、给药途径、ADR涉及的药物种类、累及的器官/系统分类、临床表现等进行统计汇总。结果新的和严重的ADR共占总数的5.73%;男女比例接近,60 a以上中老年患者893例,占总数42.28%;静脉给药1 694例,占总数80.21%;引起ADR前3位的药物为左氧氟沙星、阿奇霉素、环丙沙星;ADR临床表现主要为皮肤及其附件损害。结论应加强ADR的重点监测、主动监测和前瞻性监测工作,尽可能减少ADR的发生。
Objective To study and analyze the occurrence of ADR in the hospital, and provide the reference for clinical rational drug application. Methods A total of 2 112 ADR reports from 2005 to 2011 were collected. The ADR reports were analyzed in respects of report people, type, patients＇ condition, route of administration, the drug classification involved organs/system and the clinical manifestation. Results Among the 2 112 ADR reports, the new and severe ADR accounts for 5.73% , the ratio of men is close to women. 893 cases（42.28% ） were over 60 yeas old, 1 694 cases received intravenous administration （80. 21% ）. The top 3 drugs caused ADR include levofloxacin, azithromycin, ciprofloxacin. Lesions of skin and its appendix were the main clinical manifestations. Conclusion Intensive, active and prospective supervision should be strengthened to reduce the occurrence of ADR.
出处
《今日药学》
CAS
2013年第4期239-242,共4页
Pharmacy Today
关键词
药品不良反应
分析
监测
adverse drug reactions
analysis
monitoring
