期刊文献+

液相色谱-串联质谱法测定牛奶中11种光引发剂残留量 被引量:6

Determination of 11 Photo-initiators Residues in Milk by Liquid Chromatography-Tandem Mass Spectrometry
下载PDF
导出
摘要 建立了牛奶中11种光引发剂残留的定性和定量测定分析方法。样品经Carrez试剂沉淀蛋白质后,使用乙腈提取,HLB固相萃取柱净化,乙腈洗脱,洗脱液用氮气吹干后用50%乙腈水溶液定容,采用液相色谱-串联质谱进行测定。分析物采用电喷雾电离,正离子扫描,多反应监测(MRM)模式检测,其中7种光引发剂使用内标法定量,4种光引发剂使用外标法定量。11种光引发剂在5.00~200μg/L浓度范围内线性关系良好,相关系数均大于0.990。11种光引发剂的测定低限均为1.0μg/kg。在添加浓度1.00~100μg/kg范围内,加标回收率为74.3%~112%,相对标准偏差为0.57%~16.3%。本方法简便、有效、灵敏,适用于牛奶中光引发剂多残留的定量测定和确证。 A method for the qualitative and quantitative determination of 11 photoinitiators residues in milk by liquid chroma-tography-tandem mass spectrometry (LC-TMS) was developed.The samples were extracted with acetonitrile after being precipi-tated by Carrez reagent, and then cleaned by HLB solid phase extraction cartridge .The analytes were eluted by acetonitrile , and then reconstituted by 50%acetonitrile aqueous solution after being dried by nitrogen gas .LC-TMS was used for the determination. The analytes were determined by the mode of electro -spray ionization (ESI), positive ion scan, and multiple reaction monitoring (MRM), and internal standard method for the quantification of 7 photoinitiators and external standard method for the quantification of other 4 photoinitiators were used.Eleven photoinitiators within the concentration range of 5.00~200μg/L showed good linear re-lationship with the correlation coefficient of more than 0.990.All the lowest limits of the quantitative determination were 1.00 μg/kg.The recoveries of 11 photoinitiators were between 74.3%and 112% when the adding concentrations were 1.00~100 μg/kg, and the relative standard deviations varied from 0.57%to 16.3%.This method was simple, effective and sensitive, and suitable for the quantitative determination and confirmation of photoinitiator residues in milk .
出处 《江西农业学报》 CAS 2013年第7期94-97,101,共5页 Acta Agriculturae Jiangxi
基金 深圳出入境检验检疫局课题(SZ2008026)
关键词 液相色谱-质谱 牛奶 光引发剂 残留 LC-TMS Milk Photoinitiator Residue
  • 相关文献

参考文献2

二级参考文献15

  • 1杨保平,崔锦峰,陈建敏,周惠娣.自由基型高分子光引发剂的研究进展[J].涂料工业,2005,35(1):36-42. 被引量:16
  • 2邓晓军,郭德华,李波,朱坚,殷平.气相色谱-质谱法测定乳制品中光引发剂异丙基硫杂蒽酮的残留量[J].色谱,2007,25(1):39-42. 被引量:22
  • 3GB9685-2003食品容器、包装材料用助剂使用卫生标准[S].
  • 4Europe Food Safty Authority. Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a Request from the Commission Related to 2-Isopropyl Thioxanthone (ITX) and 2-Ethylhexyl-4- Dimethylaminobenzoate(EHDAB) in Food Contact Materials [ R/OL]. 2005 - 12 -07. http: //www. Efsa. europa. eu/ en/science/afc/afc_ opinions/1256. html.
  • 5KATAR L L. Migration from Food Contact Materials[ M]. Chapman & Hall, UK: 1996: 263.
  • 6Nestle Company. Nestle and the ITX Recall[ EB/OL]. 2005 -11 -24. http: //www. nestle. com/Media_ Center/ITX recall 23 Nov05. htm
  • 7Europe Food Safety Authority. EFSA Undertakes Risk Assessment on ITX[R/OL]. 2005 - 11 -24. http://www. efsa. europa. eu/ press_room/press_statements/1226_en. html.
  • 8PAPILLOUD S, BAUDRAZ D. Analysis of food packaging UV inks for chemicals with potential to migrate into food simulants[J]. Food Addit Contam, 2002, 19: 168.
  • 9MORLOCK G, SCHWACK W. Determination of isopropyhhioxanthone(ITX) in milk, yoghurt and fat by HPTLC - FLD, HPTLC- ESI/MS and HPTLC- DART/MS[J]. Anal Bioanal Chem, 2006, 385:586 -595.
  • 10Nestlé Company.Nestlé and the ITX Recall.2005-11-24.http://www.nestle.com/Media_Center/ITXrecall23Nov05.htm

共引文献25

同被引文献90

引证文献6

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部