摘要
目的探讨同心圆硬化的临床特征、影像学表现、治疗及预后。方法回顾性分析6例同心圆硬化患者的临床表现、影像学特征、病理结果、治疗及随访。结果 6例患者中,男4例、女2例,年龄23~63岁（平均发病年龄为41.8岁）。均呈急性或亚急性起病。首发症状：主要为偏侧肢体无力3例;其他临床症状：包括共济失调3例,智能减退2例,反应迟钝2例,病理征阳性3例。头颅MRI检查有同心圆样特征性改变。3例行立体定向脑组织活检,病理检查证实符合同心圆硬化改变。结论同心圆硬化常急性或亚急性起病,以运动障碍、精神异常、智能减退为主要临床表现,MRI检查有诊断价值,激素治疗常有效,预后多良好。
Aim To study clinical manifestations, imaging, therapy and prognosis of the Baló’s concentric sclerosis （BCS）. Methods Clinical manifestations, imaging, pathology, therapy and follow-up of 6 cases of BCS were analyzed retrospectively. Results The 6 cases, 4 male and 2 female, ranged from 23 to 63 years old （mean 41.8 years）, developed acute or subacute onset of different clinical features. Hemiparesis was the most common initial symptom, and other common symptoms included ataxia （3 cases）, hypophrenia （2 cases）, lag in response （2 cases） and positive pyramidal sign （3 cases）. Conclusion BCS developed acute or subacute onset. Its common symptoms were movement disorders, insanity and hypophrenia. MRI is helpful to diagnose, corticosteroid therapy may have effect and good prognosis.
出处
《中国临床神经科学》
2013年第4期408-412,共5页
Chinese Journal of Clinical Neurosciences
关键词
同心圆硬化
临床特点
磁共振成像
concentric sclerosis
clinical feature
magnetic resonance imaging
